Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: There is debate about the causes of the recent birth rate decline in high-income countries worldwide. During the pandemic, concern about the effects on reproductive health has caused vaccine hesitancy. We investigated the association of SARS-CoV-2 vaccination and infection with involuntary childlessness.
Methods: Females in fertility age within a prospective multicenter cohort of healthcare workers (HCW) were followed since August 2020. Data on baseline health, SARS-CoV-2-infection, and vaccination were obtained and regularly updated, in which serum samples were collected repetitively and screened for anti-nucleocapsid and anti-spike antibodies. In October 2023, participants indicated the presence of involuntary childlessness with onset during the pandemic, whereas those indicating an onset before the pandemic were excluded. The association of involuntary childlessness and SARS-CoV-2-vaccination and infection was investigated using univariable and multivariable analysis. Sensitivity analysis was performed to compare those reporting involuntary childlessness with those birthing a child since 2020.
Results: Of 798 participants, 26 (3.2%) reported involuntary childlessness starting since the pandemic. Of the involuntary childless women, 73.1% (19/26) were vaccinated compared to 86.0% (664/772) without involuntary childlessness (p = 0.73). SARS-CoV-2 infection was reported by 76.9% (20/26) compared to 72.4% (559/772) of controls (p = 0.64). Neither SARS-CoV-2 vaccination (aOR 0.91 per dose, 95%CI 0.67-1.26) nor infection (aOR per infection 1.05, 95%CI 0.62-1.71) was associated with involuntary childlessness. Sensitivity analysis confirmed these results.
Conclusions: Among female HCW of fertility age, 3.2% indicated involuntary childlessness, which is comparable to pre-pandemic data. No association between involuntary childlessness and SARS-CoV-2 vaccination or infection was found.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11157148 | PMC |
| http://dx.doi.org/10.1111/irv.13333 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Study Question: Can patient age and ovarian reserve tests predict the number of cryopreserved oocytes in patients undergoing one or more ovarian stimulation cycles for elective oocyte cryopreservation (EOC)?
Summary Answer: A predictive model incorporating patient age, antral follicle count (AFC), anti-Müllerian hormone (AMH), and FSH levels achieved the greatest predictive accuracy.
What Is Known Already: As a consequence of societal evolution, women are increasingly delaying starting a family. However, the natural decline in ovarian reserve and oocyte quality as age advances can increase the risk of age-related fertility decline (ARFD) and involuntary childlessness.
The effects of microlearning on the fertility knowledge and attitude of Iranian nursing students: an interventional study.
BMC Nurs
August 2025
Department of Nursing, School of Nursing, Alborz University of Medical Sciences, Karaj, IR, Iran.
Introduction: Despite the fact that fertility awareness is essential for making informed reproductive decisions, fertility training is still ignored in reproductive health guidelines. It is assumed that by improving fertility knowledge among students as important members of health care providers and also people who will experience parenthood soon, involuntary childlessness and the personal and social cost of infertility will decrease. This study aimed to create educational content and also explore how microlearning influences the knowledge and fertility attitudes of both male and female nursing students.
View Article and Find Full Text PDFSubfertility and infertility are stigmatising conditions impacting on the gender identity of its sufferers. Consequently, heterosexual couples undergoing fertility treatment find it difficult to disclose their condition. While research suggests that fertility treatment is an isolating and stressful experience for both partners, there is sparse literature investigating what support mechanisms exist.
View Article and Find Full Text PDFINVOLUNTARY CHILDLESSNESS AND ASSISTED CONCEPTION: PERCEPTION AMONGST NURSES AT THE UNIVERSITY COLLEGE HOSPITAL, IBADAN.
Ann Ib Postgrad Med
December 2024
Department of Obstetrics and Gynaecology, College of Medicine, University of Ibadan.
Introduction: Involuntary childlessness, a pas de deux is perceived as a stigma in many developing countries and often leads to marital disharmony due to the high premium placed on childbearing emanating from deep rooted socio-cultural beliefs. Nurses play a pivotal role in patient management due to their close contact and association with patients and their relatives. A nexus therefore exists in the uptake of clinical services by patients because of the disposition of nurses towards certain services.
View Article and Find Full Text PDFMaking and disposing of life's 'starting materials': A focus group study of attitudes concerning reproductive scarcity and abundance in in vitro gametogenesis.
Soc Sci Med
August 2025
The Institute for Society and Genetics, University of California, Los Angeles, CA, 90095, USA; Department of Sociology, University of California Los Angeles, Los Angeles, CA, 90095, USA; Center for Reproductive Science, Health, and Education, University of California, Los Angeles, CA, 90095, USA. El
This paper explores stakeholder attitudes toward gametes and embryos in the context of in vitro gametogenesis (IVG), a new stem cell technology whose future clinical application would entail the production of eggs and sperm in vitro. A key concern raised by the prospect of making gametes from originally non-reproductive body cells has been its potential exacerbation of the issue of "surplus" cryopreserved embryos through the production of unprecedented numbers, with an allied devaluation of human reproductive materials. However, this concern has not been empirically investigated.
View Article and Find Full Text PDF