Publications by authors named "Stephan Goppel"

Purpose: As healthcare workers (HCW) have been disproportionally affected by COVID-19, its post-acute sequelae (PASC) in HCW can impact healthcare systems. We assessed the burden and course of PASC in HCW over a 30-month period.

Methods: In a prospective multicentre HCW cohort in Switzerland, PASC surveys were conducted in 03/2021, 09/2021, 06/2022, 04/2023, and 10/2023.

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Article Synopsis
  • The study investigated the prevalence and risk factors for gut colonization by antibiotic-resistant bacteria in healthcare workers in Northeastern Switzerland.
  • Approximately 1,209 employees participated, revealing a 5.4% prevalence of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) and 0.1% for carbapenemase-producing Enterobacterales (CPE); no vancomycin-resistant enterococci (VRE) were found.
  • Key risk factors for ESBL-E colonization included non-European ethnicity, travel to high-risk countries, systemic antibiotic use, antibiotic eye drops, and monthly sushi consumption, while alcohol consumption was negatively associated.
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Background: There is debate about the causes of the recent birth rate decline in high-income countries worldwide. During the pandemic, concern about the effects on reproductive health has caused vaccine hesitancy. We investigated the association of SARS-CoV-2 vaccination and infection with involuntary childlessness.

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Aims Of The Study: We aimed to assess the extent of SARS-CoV-2 humoral immunity elicited by previous infections and/or vaccination among healthcare workers, and to identify reasons why healthcare workers decided against vaccination.

Methods: This nested cross-sectional study included volunteer healthcare workers from 14 healthcare institutions in German-speaking Switzerland. In January 2021, SARS-CoV-2 vaccines were available for healthcare workers.

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Background: Disentangling the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and vaccination on the occurrence of post-acute sequelae of SARS-CoV-2 (PASC) is crucial to estimate and reduce the burden of PASC.

Methods: We performed a cross-sectional analysis (May/June 2022) within a prospective multicenter healthcare worker (HCW) cohort in north-eastern Switzerland. HCWs were stratified by viral variant and vaccination status at time of their first positive SARS-CoV-2 nasopharyngeal swab.

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