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http://dx.doi.org/10.14423/SMJ.0000000000001690 | DOI Listing |
Diagn Interv Radiol
September 2025
LMU University Hospital, LMU Munich, Department of Radiology, Munich, Germany.
Purpose: Computed tomography fluoroscopy (CTF)-guided biopsy is an established technique for sampling pulmonary lesions, particularly with the growing prevalence of lung nodule screening programs. This study investigated procedural and lesion-related factors affecting success and complication rates in routine CTF-guided lung core-needle biopsies at a tertiary center.
Methods: Consecutive patients undergoing percutaneous CTF-guided lung biopsies over a 10-year period (2007-2016) were retrospectively analyzed.
Background: Advancements in healthcare have significantly improved the prospect of patients with CHD, with over 97% now surviving adulthood. This growing population requires lifelong care and support to manage their condition. Digital health innovations, such as the "Ask Me Anything" (AMA) tool, aim to empower patients and improve collaboration with clinicians.
View Article and Find Full Text PDFPeriodontol 2000
September 2025
Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Oral cancer is a major global health burden, ranking sixth in prevalence, with oral squamous cell carcinoma (OSCC) being the most common type. Importantly, OSCC is often diagnosed at late stages, underscoring the need for innovative methods for early detection. The oral microbiome, an active microbial community within the oral cavity, holds promise as a biomarker for the prediction and progression of cancer.
View Article and Find Full Text PDFJ Phys Chem B
September 2025
Department of Physical Chemistry, Gdańsk University of Technology, Narutowicza St 11/12, Gdańsk 80-233, Poland.
G-quadruplexes (G4) are four-stranded nucleic acid structures formed within sequences containing repeated guanine tracts separated by intervening loop regions. Abundant in the human genome, they play crucial roles in transcription regulation and genome maintenance. Although theoretically capable to adopt 26 different folding topologies─primarily differing in loop arrangements─only 14 of these have been observed experimentally.
View Article and Find Full Text PDFJ Biopharm Stat
September 2025
Genentech, Inc., Data and Statistical Sciences, South San Francisco, California, USA.
When animals are used in a preclinical experiment, ethical concerns may arise regarding animal welfare. The 3Rs principles were developed to guide more humane animal research practices. This article specifically addresses the reduction aspect of the 3Rs.
View Article and Find Full Text PDF