Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cels.2024.05.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Simple Solution for a Complex Problem: The "Sterile Cockpit" to Improve Ward Rounds.
World J Surg
September 2025
Department of Surgery, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia.
Background: Ward-round quality impacts patient outcomes, and poor conduct results in increased rates of preventable adverse events. Despite being a core component of patient outcomes, there is minimal literature informing best practice. The aviation industry has mitigated human error using a "Sterile Cockpit" to reduce interruptions and non-essential activities.
View Article and Find Full Text PDFPrecise measurement of motor neuron dysfunction in Drosophila ALS model via climbing assay and leg imaging.
Methods Cell Biol
September 2025
The HIT Center for Life Sciences, Harbin Institute of Technology, Harbin, P.R. China; Medical and Health Research Institute, Zhengzhou Research Institute of HIT, Zhengzhou, HA, P.R. China. Electronic address:
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disorder characterized by progressive degeneration of motor neurons, leading to muscle weakness, paralysis, and death. While there is a plethora of studies focusing on many aspects of ALS, the pathogenesis of this disease is not well understood, and effective treatments are scarce. Drosophila melanogaster is a powerful model organism for studying ALS due to its genetic tractability and its evolutionarily conserved cellular and molecular processes which are also shared between the fly and human.
View Article and Find Full Text PDFLong-wavelength emission carbon dots as ratiometric fluorescent and colorimetric dual-mode sensors for environmental sensing and bioimaging of hypochlorite.
J Hazard Mater
August 2025
Institute of Environmental Science, School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, PR China. Electronic address:
For the first time, long-wavelength red emission carbon dots (R-CDs) were prepared as ratiometric fluorescent and colorimetric dual-mode sensors for detecting ClO using a simple one-step hydrothermal method. R-CDs exhibited intrinsic red fluorescence at 587 nm. Upon interaction with ClO, a new and enhanced green fluorescence at 535 nm was observed, which was attributed to resulting from the oxidation of surface hydroxyl (-OH) groups to carbonyl (CO) groups.
View Article and Find Full Text PDFModel-driven meta-analysis establishes a new consensus view: Inhibitory neurons dominate BOLD-fMRI responses.
Comput Biol Med
September 2025
Department of Biomedical Engineering, Linköping University, Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden; School of Medical Sciences and Inflammatory Response and Infection Susceptibility Centre (iRiSC), Faculty of Medicine
Functional magnetic resonance imaging (fMRI) is a pivotal tool for mapping neuronal activity in the brain. Traditionally, the observed hemodynamic changes are assumed to reflect the activity of the most common neuronal type: excitatory neurons. In contrast, recent experiments, using optogenetic techniques, suggest that the fMRI-signal could reflect the activity of inhibitory interneurons.
View Article and Find Full Text PDFBlood-based DNA methylation markers for autism spectrum disorder identification using machine learning.
Epigenomics
September 2025
College of Physical Education, Yangzhou University, Yangzhou, China.
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder lacking objective biomarkers for early diagnosis. DNA methylation is a promising epigenetic marker, and machine learning offers a data-driven classification approach. However, few studies have examined whole-blood, genome-wide DNA methylation profiles for ASD diagnosis in school-aged children.
View Article and Find Full Text PDF