Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The presence of phytotoxins in plants constitutes a health risk for herbivores, particularly on ruminants who accidently consume them. Among the adverse effects produced by these are reproductive alterations, represented by abortion, infertility, and morphological alterations in neonates, which are frequently attributed to other causes. While in some cases the plants that contain such metabolites are known, other times they are not, leading to alterations that are difficult to treat considering that their toxicodynamics are unknown. The objective of this documentary research is to provide information on how metabolites such as phytoestrogens, L-mimosine, labdane diterpenoids - isocupressic acid, quinolizidine alkaloids and piperidine swainsonine, anabasine, coniine and associated alkaloids, among others, exert their action in the animal organism and the effects they produce.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.toxicon.2024.107769 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Experimental deepening of the winter snowpack reduces fine root standing crop at treelines in northwest Alaska.
New Phytol
September 2025
Environment and Natural Resources Institute, University of Alaska Anchorage, Anchorage, AK, 99508, USA.
Snow is an important insulator of Arctic soils during winter and may be a source of soil moisture in summer. Changes in snow depth are likely to affect fine root growth and mortality via changes in soil temperature, moisture, and/or nutrient availability, which could alter aboveground growth and reproduction of Arctic vegetation. We explored fine root dynamics at three contrasting treelines in northwest Alaska.
View Article and Find Full Text PDFJinggangmycin-induced NlPR-L and NlABD4-L genes regulate fecundity in the brown planthopper, Nilaparvata lugens (Stål) (Hemiptera: Delphacidae).
Pestic Biochem Physiol
November 2025
College of Plant Protection, Yangzhou University, 225009 Yangzhou, PR China. Electronic address:
The brown planthopper (BPH), Nilaparvata lugens (Stål), is a typical insecticide-induced resurgence rice pest that causes severe damage to rice in Asian countries. Previous studies have shown that the fungicide Jinggangmycin (JGM), used to control rice sheath blight disease, can stimulate BPH fecundity; however, the molecular mechanism remains to be further explored. In this study, based on transcriptomic analysis, we found that the PI3K-Akt signaling pathway was significantly enriched in BPH after feeding on JGM-treated rice, where the NlPR-L and NlABD4-L genes were significantly upregulated.
View Article and Find Full Text PDFAluminum exposure disturbs epigenetic modification and organelle function during early embryo development.
Chem Biol Interact
September 2025
Key Laboratory of Research on Clinical Molecular Diagnosis for High Incidence Diseases in Western Guangxi of Guangxi Higher Education Institutions, Reproductive Medicine of Guangxi Medical and Health Key Discipline Construction Project, Affiliated Hospital of Youjiang Medical University for National
Aluminum is a lightweight and corrosion-resistant metal element that is widely used in industries, construction, food, and pharmaceuticals, and it can adversely affect multiple organ systems including the nervous system, skeletal system, reproductive system, blood system, and immune system. In present study, we investigated the effects of aluminum exposure on mammalian embryo development. Our data demonstrate that aluminum exposure induces mouse early embryo development defects, including those at the zygotes and 2-cell stages, causing a decrease in general transcription activity.
View Article and Find Full Text PDFResponses of different life stages of Physa acuta (Draparnaud, 1805) to the pesticides imidacloprid and tebuconazole: effects on growth, reproduction, and behavior.
Aquat Toxicol
September 2025
University of Campinas (UNICAMP), Institute of Chemistry, Campinas, São Paulo, Brazil.
Aquatic pollution caused by pesticides raises concerns about the effects on wildlife. While risk assessment protocols with invertebrates focus mainly on arthropods, the effects on gastropods are underexplored. In this way, the impact of exposure to imidacloprid, a neonicotinoid insecticide, and tebuconazole, an azole fungicide, on different life stages of the freshwater snail Physa acuta was investigated.
View Article and Find Full Text PDFPatient-Specific Regulatory Network Rewiring in Inflammatory Bowel Disease: How Genetic Polymorphisms Divert Incoming Signals and Contribute to Disease Pathogenesis.
Inflamm Bowel Dis
September 2025
Gut Microbes and Health Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich, United Kingdom.
Background: Intestinal cells receive incoming signals from neighboring cells and microbial communities. Upstream signaling pathways transduce these signals to reach transcription factors (TFs) that regulate gene expression. In inflammatory bowel disease (IBD), most single nucleotide polymorphisms (SNPs) are in non-coding genomic regions containing TF binding sites.
View Article and Find Full Text PDF