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Background: The European Union (EU) faces many health-related challenges. Burden of diseases information and the resulting trends over time are essential for health planning. This paper reports estimates of disease burden in the EU and individual 27 EU countries in 2019, and compares them with those in 2010.
Methods: We used the Global Burden of Disease 2019 study estimates and 95% uncertainty intervals for the whole EU and each country to evaluate age-standardised death, years of life lost (YLLs), years lived with disability (YLDs) and disability-adjusted life years (DALYs) rates for Level 2 causes, as well as life expectancy and healthy life expectancy (HALE).
Results: In 2019, the age-standardised death and DALY rates in the EU were 465.8 deaths and 20,251.0 DALYs per 100,000 inhabitants, respectively. Between 2010 and 2019, there were significant decreases in age-standardised death and YLL rates across EU countries. However, YLD rates remained mainly unchanged. The largest decreases in age-standardised DALY rates were observed for "HIV/AIDS and sexually transmitted diseases" and "transport injuries" (each -19%). "Diabetes and kidney diseases" showed a significant increase for age-standardised DALY rates across the EU (3.5%). In addition, "mental disorders" showed an increasing age-standardised YLL rate (14.5%).
Conclusions: There was a clear trend towards improvement in the overall health status of the EU but with differences between countries. EU health policymakers need to address the burden of diseases, paying specific attention to causes such as mental disorders. There are many opportunities for mutual learning among otherwise similar countries with different patterns of disease.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110444 | PMC |
http://dx.doi.org/10.1186/s12889-024-18529-3 | DOI Listing |
Paediatr Perinat Epidemiol
September 2025
Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, China.
Background: Lower respiratory infections (LRI) are a leading cause of death among children aged 0 to 14 globally. LRI burden estimates remain incomplete, especially in resource-limited settings.
Objective: To assess the global, regional, and national burden of LRI in children, analyse trends in incidence, mortality, and disability-adjusted life-years (DALYs), and predict future burden projections from 2022 to 2035, exploring variations in major bacterial pathogens.
BMC Cancer
August 2025
Department of Gastroenterology, The First Affiliated Hospital of China Medical University, 155# North Nanjing Street, Heping District, Liaoning Province, Shenyang City,, 110001, China.
Purpose: Colorectal cancer treatment measures can lead to reduced fertility and premature ovarian failure in women of childbearing age (WCBA), resulting in a major global burden. This study aimed to assess the global, regional and national burden of colorectal cancer (CRC) in WCBA and to provide the most up-to-date and comprehensive information available on WCBA CRC.
Methods: Four main indicators, including prevalence, incidence, mortality, and DALYs, related to CRC in WCBA were extracted from the Global Burden of Disease (GBD) database from 1990 to 2021.
Lancet Glob Health
August 2025
Center for Health Equity in Surgery and Anesthesia, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, San Francisco, CA, USA.
Background: Globally, the burden of chronic kidney disease and ensuing need for kidney replacement therapy (KRT)-dialysis or kidney transplantation-are increasing. Despite the mortality benefit of transplantation over dialysis, dialysis services are expanding more rapidly than access to transplantation. We aimed to cross-sectionally assess the association between country-level KRT rates and chronic kidney disease mortality to facilitate evidence-based prioritisation of KRT modalities.
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August 2025
HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Objectives: To examine the global and regional trends in disparities of high systolic blood pressure (HSBP) burden between 1990 and 2021 by age, sex, sociodemographic index and health systems' performance.
Design: Systematic analysis.
Setting: Global population-level data were extracted from the Global Burden of Disease (GBD) 2021 study covering all countries, grouped by World Bank income classifications and seven GBD super-regions.
Glob Heart
August 2025
Santa Maria University Hospital, CAML, CCUL, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal.
Obesity is a growing global epidemic with significant implications for cardiovascular diseases (CVD). It couples as an independent risk factor and driver for multiple pathways leading to CVDs. Here we examine obesity's impact on CVD and propose actionable strategies.
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