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Background: Contemporary fixed orthodontic appliances are shifting from non-customized pre-adjusted appliances to custom-designed and printed appliances with novel digital setup systems. We are one step closer to precision dentistry and orthodontics using personalized mechanics and custom appliances. However, despite the evidential enhancement and other improvements to fixed appliances, tooth movement is still limited to five degrees of freedom. Opening or closing spaces still requires manually placing elastomeric chains or coil springs.
Aim: In this article, we aimed to demonstrate how advancements in CAD/CAM technology, reverse engineering, and digital customization are helping orthodontics constantly evolve, enabling treatment with enhanced esthetics and minimal compliance. The clinical system (InBrace®, Irvine, CA) described in this article uses a patient-specific, digitally designed multiloop NITI wire that delivers friction-free, light, and continuous forces and activates automatically whenever the malocclusion deviates from the digital setup.
Conclusion: Through digital customization, InBrace allows for automated tooth movement in all six degrees of freedom, including space opening or closure, via programmed non-sliding mechanics.
Clinical Significance: Precision orthodontics and personalized treatment have been significant developments in orthodontics recently. This article focuses on how a technologically advanced lingual appliance system could achieve targeted cosmetic results methodically via automation and personalization.
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http://dx.doi.org/10.1111/jerd.13244 | DOI Listing |
J Prosthet Dent
September 2025
Associate Professor, Department of Dental Surgery, Faculty of Dental Surgery, University of Malta, Malta. Electronic address:
A digital workflow merging root submergence, immediate dental implant and definitive intermediate abutment placements, and custom healing abutment fabrication to enhance esthetic and biological outcomes in immediate implant procedures is described. The procedure involves a prosthetically driven plan on intraoral and cone beam computed tomography (CBCT) scans, digital planning using a specialized software program, the creation of a surgical guide, and the digital design of custom components. A 3-dimensionally (3D) printed healing abutment was produced by following specific protocols.
View Article and Find Full Text PDFBone Jt Open
September 2025
Kadoorie, Oxford Trauma and Emergency Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford University, Oxford, UK.
Aims: We sought to explore staff experience of a paediatric randomized controlled trial (RCT), comparing operative fixation and nonoperative treatment for displaced medial epicondyle fractures.
Methods: A total of 20 staff (eight surgeons and 12 research delivery staff) recruiting to the RCT in 18 NHS Trusts across the UK took part in a telephone/online qualitative interview. Interviews were informed by Heideggerian Phenomenology and thematic analysis.
Microb Pathog
September 2025
Laboratory of Food and Environmental Hygiene, Joint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan; Joint Graduate School of Veterinary Sciences, Gifu University,1-1 Yanagido, Gifu 501-1193, Japan; Education and Research
Campylobacter jejuni is the leading cause of foodborne illness in humans, typically after consuming contaminated chicken meat, and it holds significant public health importance. C. jejuni enters viable but non-culturable (VBNC) state in response to various environmental stressors, including low temperatures and nutrient starvation.
View Article and Find Full Text PDFJMIR Med Inform
September 2025
Departments of Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, Guangdong, 510630, China, 86 18922109279, 86 20852523108.
Background: Despite the Coronary Artery Reporting and Data System (CAD-RADS) providing a standardized approach, radiologists continue to favor free-text reports. This preference creates significant challenges for data extraction and analysis in longitudinal studies, potentially limiting large-scale research and quality assessment initiatives.
Objective: To evaluate the ability of the generative pre-trained transformer (GPT)-4o model to convert real-world coronary computed tomography angiography (CCTA) free-text reports into structured data and automatically identify CAD-RADS categories and P categories.
Food Res Int
November 2025
College of Animal Sciences, Zhejiang University, Hangzhou, China; Key Laboratory of Molecular Animal Nutrition (Zhejiang University), Ministry of Education, China. Electronic address:
Cultured meat is an emerging field in future food production, employing interdisciplinary strategies that integrate the food industry, tissue engineering, and biotechnology to meet global food needs. Cultivating meat from stem cells is an increasingly recognized solution to address concerns associated with animal husbandry in terms of environment, health, and ethics. Despite significant advances, substantial technical challenges persist.
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