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Aims: This study aims to investigate the trends in treatment coverage through dispensing diabetes medications in Vietnam from 2015 to 2021. The findings will serve to inform health policies to mitigate the health burden of Type 2 diabetes mellitus (T2DM).
Methods: We collected information on major antidiabetic medicines from General Department of Vietnam Customs and payments for antidiabetics via the National Health Insurance Program. We applied ordinary least squares models, accounting for economic and health outcome characteristics, to estimate the association between the annual mass of medications and related factors.
Results: Nationally, the total mass/doses of all antidiabetic drugs increased rapidly from 2015 to 2021, based on both databases. Metformin was the most frequently prescribed medicine, with the total mass increasing nearly threefold over the study period. Gliclazide, a Sulfonylureas drug, ranked second. In the multivariate regression analysis, a one-unit increase in adults with diabetes (in 1,000 s) was associated with 0.11 % (95 %CI = 0.0005; 0.0076) and 0.13 % (95%CI = 0.0007; 0.0242) higher mass of Metformin and Glimepiride, respectively.
Conclusion: Our data suggested that policies changes were related to significant increase in antidiabetic medication dispenses in Vietnam. The high treatment coverage indicates impressive progress in achieving universal health coverage in Vietnam, meeting the UN Sustainable Development Goal (SDG).
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http://dx.doi.org/10.1016/j.diabres.2024.111691 | DOI Listing |
Soc Psychiatry Psychiatr Epidemiol
September 2025
Department of Psychology, Harvard University, Cambridge, MA, USA.
Purpose: Hatzenbuehler's psychological mediation framework proposes that difficulties in emotion regulation (ER), which are driven in part by excess exposure to stigma-related experiences, contribute to sexual orientation-related mental health disparities. However, existing research on the framework has largely focused on a small number of ER variables in non-probability samples.
Methods: To address these limitations, we examined whether a large complement of ER components mediates the prospective association between sexual minority status and depressive symptoms, using longitudinal data from a population-based sample of 1,208 Swedish young adults (aged 18-35).
Adv Child Dev Behav
September 2025
Department of Psychology, Northwestern University, Evanston, IL, USA. Electronic address:
In the past few decades, interest in children's spatial thinking has increased substantially, and consequently, interest in spatial assessments for children has also increased. However, there are not many reliable, validated, and widely accessible spatial assessments for this segment of the population, which affects researchers' ability to conduct and interpret spatial thinking research. While some limitations of these tests relate to broader issues with spatial assessments in general (see Uttal et al.
View Article and Find Full Text PDFJ Neurosurg
September 2025
1Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Objective: In this retrospective study, authors aimed to evaluate the glymphatic function alterations associated with glioma and explore the prognostic value of these alterations by calculating the index for diffusivity along the perivascular space (ALPS index).
Methods: The authors utilized data from the publicly available University of California San Francisco Preoperative Diffuse Glioma MRI (UCSF-PDGM) dataset, which includes 501 adult patients with histopathologically confirmed diffuse glioma, per the 2021 WHO classification, who underwent preoperative MRI, initial tumor resection, and tumor genetic testing at a single medical center from 2015 to 2021.The ALPS index was calculated from diffusivity maps for noninvasive glymphatic system (GS) analysis.
J Neurosurg Spine
September 2025
1Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Objective: The evidence on ankylosing spinal disorders (ASDs), including ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH), in the context of spinal fracture stems from studies with relatively small sample sizes. There are no studies addressing the patient-reported outcome measures (PROMs) and health-related quality of life (HRQOL) outcomes associated with spinal fracture in this population. The aim of this study was to investigate differences in complications, mortality, PROMs, and HRQOL in patients with and without ASD who had been treated for spinal fracture.
View Article and Find Full Text PDFJ Neurosurg Spine
September 2025
1Department of Neurological Surgery, Rush University Medical Center, Chicago; and.
Objective: Spondylodiscitis is classically believed to reflect intravenous drug use in urban centers, hemodialysis-associated complications, and generalized poor medical care, but these associations may be more complex and reflect underlying systemic societal problems. The authors sought to characterize socioeconomic and demographic elements associated with spondylodiscitis to better understand community factors placing patients at risk of this infection.
Methods: All cases of spondylodiscitis at an urban, tertiary-level academic hospital since 2015 were surveyed.