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Purpose Of Review: This review focuses on the challenges of diagnosing and treating spontaneous intracranial hypotension (SIH), a condition caused by spinal CSF leakage. It emphasizes the need for increased awareness and advocates for early and thoughtful use of empirical epidural blood patches (EBPs) in suspected cases.
Recent Findings: SIH diagnosis is hindered by variable symptoms and inconsistent imaging results, including normal brain MRI and unreliable spinal opening pressures. It is crucial to consider SIH in differential diagnoses, especially in patients with connective tissue disorders. Early EBP intervention is shown to improve outcomes.
Summary: SIH remains underdiagnosed and undertreated, requiring heightened awareness and understanding. This review promotes proactive EBP use in managing suspected SIH and calls for continued research to advance diagnostic and treatment methods, emphasizing the need for innovative imaging techniques for accurate diagnosis and timely intervention.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11065326 | PMC |
http://dx.doi.org/10.1212/CPJ.0000000000200290 | DOI Listing |
Front Neurol
August 2025
Department of Neurology, Cleveland Clinic Florida/Martin Health, Port Saint Lucie, FL, United States.
Importance: Current guidelines recommend against the routine use of seizure prophylaxis in acute spontaneous intracerebral hemorrhage (sICH).
Objective: The goal of this study is to evaluate if the use of prophylactic levetiracetam resulted in reduced incidence of seizure, morbidity, and length of stay, compared to patients who did not receive prophylactic levetiracetam.
Design: This retrospective chart review includes patients admitted with ICH at Cleveland Clinic Florida Martin Health from January 2019 to October 2022.
J Clin Neurosci
September 2025
Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital Hsin-Chu Branch, Hsin-chu, Taiwan; Department of Physical Medicine and Rehabilitation, College of Medicine, National Taiwan University Hospital, National Taiwan University, Taiwan. Electronic address: b96401093@n
Objectives: The aim of this study is to investigate the association between masticatory muscle thickness and dysphagia in intracerebral hemorrhage (ICH) patients.
Materials & Methods: This retrospective cohort study included patients with spontaneous ICH confirmed by brain computed tomography (CT) between June 2019 and June 2024 in a university-affiliated hospital. Temporal muscle thickness (TMT) and masseter muscle thickness (MMT) were measured on the initial brain CT.
Front Med (Lausanne)
August 2025
Department of General Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei, China.
Horner syndrome (HS), a rare complication of endoscopic thyroid surgery (ETS), manifests as ptosis, miosis, and anhidrosis resulting from oculosympathetic pathway disruption. This study explores HS etiology through two case reports and literature analysis. Case 1 involved a 43-year-old female who underwent unilateral thyroidectomy via a bilateral areolar approach for a thyroid oncocytic adenoma.
View Article and Find Full Text PDFCancer Diagn Progn
September 2025
Department of Orthopaedic Surgery, Hiroshima University, Hiroshima, Japan.
Background/aim: Metastases of meningiomas are infrequent, and extracranial bone involvement is extremely rare. We describe a patient with femoral metastasis originating from an atypical brain meningioma.
Case Report: A 55-year-old male had undergone five surgical procedures and Gamma Knife® radiosurgery for brain meningioma over five years.
Otol Neurotol
August 2025
Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine.
Objective: Determine if class 3, morbid obesity (body mass index, BMI >40 kg/m2) patients have increased risk of complications following middle cranial fossa (MCF) repairs of spontaneous cerebrospinal fluid leaks (sCSF-Ls).
Study Design: Retrospective cohort.
Setting: Tertiary academic.