Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s12640-024-00701-7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Correction: Effects of Gap 26, a Connexin 43 Inhibitor, on Cirrhotic Cardiomyopathy in Rats.
Cureus
August 2025
Pharmacology, Tehran University of Medical Sciences, Tehran, IRN.
[This corrects the article DOI: 10.7759/cureus.59053.
View Article and Find Full Text PDFCorrection: Bee gomogenat enhances the healing process of diabetic wounds by orchestrating the connexin-pannexin gap junction proteins in streptozotocin-induced diabetic mice.
Sci Rep
July 2025
Mallawi Specialized Hospital, 26Th of July Street, Mallawi, Minia, Egypt.
Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification.
Biol Open
August 2025
University of Geneva, Faculty of Medicine, Department of Pathology and Immunology, Rue Michel-Servet 1, Geneva 4, Switzerland.
Haematopoietic stem and progenitor cells (HSPCs) derive from a subset of endothelial cells (ECs), known as haemogenic ECs by the process of endothelial-to-haematopoietic transition (EHT). Although many factors involved in EHT have been elucidated, we still have a poor understanding of the temporal regulation of this process. Mitochondrial-derived reactive oxygen species (ROS) have been shown to stabilise the hypoxia-inducible factor 1/2α (Hif1/2α) proteins, allowing them to positively regulate EHT.
View Article and Find Full Text PDFRare and novel variant load threshold for KIF7, GJA1 and PDE1C genes elevates the risk of severity of congenital heart defects in Down syndrome.
PLoS One
June 2025
Cytogenetics-Genomics and Down syndrome Research Unit, Department of Zoology, University of Calcutta, Kolkata, West Bengal, India.
Individuals with Down syndrome (DS) exhibit a higher incidence of congenital heart defects (CHD). The objective of the present study was to investigate ethnicity-specific genetic variants that increase the risk of CHD in children with DS from the Indian Bengali population. We conducted whole exome sequencing of the genomes of Down syndrome children with and without CHD and subsequently tested the identified variants in a larger cohort (N = 1798).
View Article and Find Full Text PDFRestructures the Micro/Mycobiome to Combat Inflammation-Mediated Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
Circ Heart Fail
July 2025
Lillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis (S.Z.P., M.B., F.K., R.M., B.P.K., L.M.H., M.K., N.V., J.B.M., T.T., K.W.P.).
Background: Inflammation suppresses right ventricular (RV) function in pulmonary arterial hypertension (PAH). In particular, we showed GP130 (glycoprotein-130) signaling promotes pathological microtubule remodeling and RV dysfunction in rodent PAH. Emerging data demonstrate the intestinal microbiome regulates systemic inflammation, but the impact of modulating the gut microbiome on the GP130-microtubule axis in RV failure is unknown.
View Article and Find Full Text PDF