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http://dx.doi.org/10.1253/circj.CJ-24-0139 | DOI Listing |
Radiology
September 2025
Department of Magnetic Resonance Imaging, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background MRI-derived arrhythmogenic substrate, including late gadolinium enhancement (LGE) and extracellular volume fraction (ECV), is indicative of sudden cardiac death (SCD) risk in nonischemic dilated cardiomyopathy (DCM). The relative prognostic value of LGE and ECV remains unclear. Purpose To evaluate the performance of LGE and T1 mapping in predicting SCD in patients with DCM and to explore clinical implementation.
View Article and Find Full Text PDFArch Esp Urol
August 2025
Department of Urology, The First People's Hospital of Jiujiang, 332000 Jiujiang, Jiangxi, China.
Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent urological condition affecting men's health. This study aims to investigate the clinical efficacy of Qianlie Shutong (QLST) capsule in the treatment of CP/CPPS.
Methods: The medical records of patients with CP/CPPS who were admitted to our hospital from January 2023 to January 2024 were retrospectively analysed.
IEEE Trans Nanobioscience
September 2025
Extracellular vesicles (EVs) produced by stem cells are nanoscale carriers of bioactive compounds with regenerative and immunomodulatory capabilities similar to those of their parent cells. Their therapeutic potential outperforms traditional stem cell therapies by lowering hazards such tumorigenicity and allowing for precise delivery. To provide a high-efficiency platform for selectively isolating stem cell EVs from minimal serum quantities while overcoming the constraints of traditional approaches such as ultracentrifugation, we developed an immunoaffinity-based capture system utilizing SiO₂ wafers functionalized with gold nanoparticles (GNPs), polyethylene glycol (HS-PEG-COOH), and stem cell-specific antibodies.
View Article and Find Full Text PDFFront Hum Neurosci
August 2025
Signal Processing Laboratory (LTS5), École Polytechnique Féderale de Lausanne (EPFL), Lausanne, Switzerland.
Introduction: Absence of language development is a condition encountered across a large range of neurodevelopmental disorders, including a significant proportion of children with autism spectrum disorder. The neurobiological underpinnings of non-verbal ASD (nvASD) remain poorly understood.
Methods: This study employed multimodal MRI to investigate white matter (WM) microstructural abnormalities in nvASD, focusing on language-related pathways.
Eur Phys J E Soft Matter
September 2025
Department of Mathematics, Indian Institute of Technology Kharagpur, Kharagpur, 721302, West Bengal, India.
Tumour growth involves dynamic interactions among tumour cells, extracellular materials, and host tissue. The tumour exerts mechanical stresses on the host tissue and simultaneously experiences compression across the tumour-host interface. This article presents a mathematical model that mimics an in vivo set-up, where an avascular tumour is surrounded by healthy/normal tissue, utilizing conservation principles for the constituents in each region.
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