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Understanding the diversity in cancer research priorities and the correlations among different treatment modalities is essential to address the evolving landscape of oncology. This study, conducted in collaboration with the European Cancer Patient Coalition (ECPC) and Childhood Cancer International-Europe (CCI-E) as part of the "UNCAN.eu" initiative, analyzed data from a comprehensive survey to explore the complex interplay of demographics, time since cancer diagnosis, and types of treatments received. Demographic analysis revealed intriguing trends, highlighting the importance of tailoring cancer research efforts to specific age groups and genders. Individuals aged 45-69 exhibited highly aligned research priorities, emphasizing the need to address the unique concerns of middle-aged and older populations. In contrast, patients over 70 years demonstrated a divergence in research priorities, underscoring the importance of recognising the distinct needs of older individuals in cancer research. The analysis of correlations among different types of cancer treatments underscored the multidisciplinary approach to cancer care, with surgery, radiotherapy, chemotherapy, precision therapy, and biological therapies playing integral roles. These findings support the need for personalized and combined treatment strategies to achieve optimal outcomes. In conclusion, this study provides valuable insights into the complexity of cancer research priorities and treatment correlations in a European context. It emphasizes the importance of a multifaceted, patient-centred approach to cancer research and treatment, highlighting the need for ongoing support, adaptation, and collaboration to address the ever-changing landscape of oncology.
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http://dx.doi.org/10.3390/curroncol31040139 | DOI Listing |
Cureus
August 2025
Plastic and Reconstructive Surgery, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, GBR.
Objectives: This study evaluates the management of paediatric melanoma at a tertiary centre, comparing clinical practices with international guidelines from the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) and the National Comprehensive Cancer Network (NCCN) to highlight real-world practices and make recommendations for future research priorities. The differences between conventional and Spitzoid melanomas were also explored in a subgroup analysis.
Background: Paediatric melanoma is rare and is most commonly caused by UV exposure or familial mutations.
Lab Anim Res
September 2025
Korea Model Animal Priority Center (KMPC), Seoul, Republic of Korea.
Background: Laboratory animal veterinarians play a crucial role as a bridge between the ethical use of laboratory animals and the advancement of scientific and medical knowledge in biomedical research. They alleviate pain and reduce distress through veterinary care of laboratory animals. Additionally, they enhance animal welfare by creating environments that mimic natural habitats through environmental enrichment and social associations.
View Article and Find Full Text PDFBehav Res Ther
September 2025
Curtin School of Allied Health, Curtin University, Perth, Australia.
Chronic low back pain (CLBP) is an urgent global health priority given its high prevalence and impact as the leading cause of disability. While several efficacious treatments exist, most have modest effects. Improving outcomes requires a better understanding of treatment mechanisms to enable optimisation.
View Article and Find Full Text PDFBMJ Public Health
September 2025
School of Public Health, University of Sydney, Sydney, New South Wales, Australia.
Introduction: Curbing adolescent vaping is a public health priority and little evidence exists examining protective factors. Using a strength-based approach, this study explored the relationship between adolescent vaping health perceptions and vaping use.
Methods: Cross-sectional data from 9000 Australian adolescents aged 14-17 years recruited via multiple online panels as part of the Generation Vape Study were used.
Health Econ Policy Law
September 2025
Department of Health Policy, London School of Economics and Political Science, London, UK.
While a substantial amount of evidence exists on factors associated with positive health technology assessment (HTA) outcomes, the evidence on the same regarding rejections is scarce. Using a proprietary dataset of HTA outcomes in seven Organisation for Economic Co-operation and Development (OECD) countries, we empirically examine the factors associated with HTA rejections and study the magnitude of inter-agency differences in technology appraisals. Data were extracted from HTA reports between 2009 and 2020.
View Article and Find Full Text PDF