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Hypopigmented scars are challenging to treat, and the focus for successful treatment is to cause pigment cells to produce more melanin. In this study, we evaluated the repigmentation effects of 0.4 mm motorized-micropunch grafting with skin-seeding for hypopigmented scars. Twenty-one patients with hypopigmented scars on the face and neck that had been resistant to conventional treatment and who had finally undergone micropunch grafting with a skin-seeding technique (SST) were retrospectively reviewed. Repigmentation outcomes were evaluated with global assessment by a physician using a 4-point repigmentation scale. Adverse events were noted. The subjects were followed for a 2-year follow-up period post grafting. All 21 subjects exhibited excellent to complete repigmentation of more than 75% of the hypopigmented scars. More than 90% repigmentation was observed in 17 patients. The mean duration for repigmentation that the subjects were satisfied with was 5.5 months. No adverse effects or recurrence instances were observed. Motorized micropunch grafting is an effective and promising alternative treatment for repigmentation of hypopigmented scars.
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http://dx.doi.org/10.1111/1346-8138.17216 | DOI Listing |
Cureus
July 2025
Dermatology, Vibrant Dermatology, Dedham, USA.
Hypopigmented scars present a cosmetic and psychological burden, especially in patients of darker skin types. Novel strategies to restore pigment are limited and often ineffective. A 48-year-old woman presented with a complaint of hypopigmented burn scars on both arms.
View Article and Find Full Text PDFBurns
July 2025
Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States; Department of Surgery, Georgetown University School of Medicine, Washington, DC, United States; The Burn Center, Department of Surgery, MedStar Washington Hospital Center, Washingto
Post-burn hypertrophic scars often exhibit dyschromia, including hyper- and hypo-pigmentation. Inactivated melanocytes, typically residing in the epidermal basement membrane, pose a challenge for effective activation and repigmentation in scarred areas. This study explores an alternative approach: using laser-assisted drug delivery to transplant melanocyte-containing cell suspensions into hypopigmented scars.
View Article and Find Full Text PDFJ Dtsch Dermatol Ges
July 2025
Clinic and Polyclinic for Dermatology, Venereology and Allergology, Leipzig University Hospital, Leipzig, Germany.
Background: Currently, there are no effective drug therapy options that lead to the regression of rhinophyma. Many surgical procedures for treating rhinophyma have been published; however, there are limited data on their effectiveness. In addition, these treatment options often lead to persistent hypopigmented scarring if excessive ablation or heat is applied.
View Article and Find Full Text PDFLasers Med Sci
January 2025
Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Niayesh Street, Sattar Khan Avenue, Rasool Akram Hospital, Tehran, Iran.
Burn scars present psychological and social challenges for patients, classified into atrophic and hypertrophic types. Treatments like corticosteroid injections, laser therapy, and platelet-rich plasma (PRP) injections are commonly recommended for hypertrophic scars, while regenerative medicine and fractional CO2 lasers are linked to some degree of improvement for atrophic scars. Hypopigmented and depigmented burn scars pose ongoing challenges for healthcare providers and patients, with therapies such as intense pulsed light and fractional CO2 laser showing variable effects in treating these conditions.
View Article and Find Full Text PDFActas Dermosifiliogr
May 2025
Servicio de Dermatología, Hospital Clínic de Barcelona, Universitat de Barcelona, Spain. Electronic address:
Although secondary intention healing (SIH) is a fundamental aspect of postoperative care following Mohs micrographic ssurgery (MMS), it is currently underutilized. SIH constitutes a safe, cost-effective, and versatile method for wound closure. SIH offers multiple advantages, including enhanced cancer surveillance, reduced pain, and promosing esthetic outcomes, particularly not only on certain anatomical regions such as the medial canthus, antihelix, temple, or alar crease, but also for relatively small and superficial defects on the eyelids, ears, lips, and nose, including the alar region, and defects on the hands dorsal regions.
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