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Benign prostatic hyperplasia (BPH) commonly occurs in middle-aged and elderly men, affecting their physical health while also triggering varying degrees of stigma. This leads to reduced treatment compliance and a lower quality of life for patients. This article elaborates on the conceptual development of stigma, the current state of stigma in BPH patients, sources and impacts of stigma, tools for investigating stigma, and intervention measures. The aim is to enhance medical professionals' understanding of stigma and provide a basis for effective nursing interventions.
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J Environ Pathol Toxicol Oncol
January 2025
Department of Biostatistics, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Prostate cancer and inflammation mechanism are closely related because chronic inflammation causes inflammatory cells to infiltrate into prostatic atrophy areas and proliferative inflammatory atrophy is accepted as the initiator of prostate cancer. The study included 90 patients (28 patients with benign prostatic hyperplasia (BPH), 35 patients with localized prostate cancer (LPCa), and 27 patients with metastatic prostate cancer (MPCa) and 90 healthy controls. Blood samples from 90 patients and 90 healthy people were used to isolate genomic DNA.
View Article and Find Full Text PDFWorld J Urol
September 2025
Sindh Medical College, Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.
Front Genet
August 2025
Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Background: Prostatic diseases, consisting of prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer (PCa), pose significant health challenges. While single-omics studies have provided valuable insights into the role of mitochondrial dysfunction in prostatic diseases, integrating multi-omics approaches is essential for uncovering disease mechanisms and identifying therapeutic targets.
Methods: A genome-wide meta-analysis was conducted for prostatic diseases using the genome-wide association studies (GWAS) data from FinnGen and UK Biobank.
CRSLS
September 2025
Faculty of Medicine, Department of Internal Medicine, Division of Intensive Care Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye. (Dr. Demirer Aydemir).
We present a rare morphological variant of a colonic polyp observed during a routine screening colonoscopy. A 62-year-old male with known chronic obstructive pulmonary disease (COPD) and benign prostatic hyperplasia (BPH) was found to have a bridge-shaped polyp in the sigmoid colon. The polyp was successfully resected via snare polypectomy following submucosal adrenaline injection.
View Article and Find Full Text PDFJ Pathol Transl Med
September 2025
Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Background: Prostate cancer is one of the most common malignancies in males worldwide. Serum prostate-specific antigen is a frequently employed biomarker in the diagnosis and risk stratification of prostate cancer; however, it is known for its low predictive accuracy for disease progression. New prognostic biomarkers are needed to distinguish aggressive prostate cancer from low-risk disease.
View Article and Find Full Text PDF