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Sickle cell disease is a hereditary red blood cell disorder characterized by hemolytic anemia, particularly in association with stress. As they grow, most children with sickle cell anemia undergo auto-splenectomy, making them vulnerable to serious infections. Patients with sickle cell disease infected with the SARS-CoV-2 virus are reported to have an increased risk for hospitalization, thrombosis, and other complications compared to non-sickle cell patients. Influenza infection in patients with sickle cell is associated with increased morbidity. Patients with sickle cell HbSC are reported to have a milder form of the disease than HbSS. Coinfection with SARS-CoV-2 and influenza B is rarely reported in patients with hematologic diseases, including sickle cell hemoglobinopathy. We are reporting an unusual case of a patient with sickle cell HbSC with co-infection of SARS-CoV-2 and influenza B with a favorable outcome.
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http://dx.doi.org/10.7759/cureus.56102 | DOI Listing |
Front Health Serv
August 2025
Department of Medical Laboratory Sciences, University of Nigeria, Enugu, Nigeria.
Introduction: In sub-Saharan Africa, the burden of sickle cell disease remains high. With annual sickle cell births of about 150,000, Nigeria is reported to have the highest prevalence of the disease globally. This study aimed to explore the views and perspectives of healthcare professionals regarding access to healthcare services for sickle cell disease.
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September 2025
Division of Respiratory Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
J Natl Med Assoc
September 2025
Communication Equity Outcomes Laboratory, Department of Speech, Language and Hearing Sciences, University of Florida, Gainesville, FL, United States.
Importance: Significant advancements have been made in the management of sickle cell disease (SCD); an inherited blood disorder most prevalent among African Americans. While chronic pain is a hallmark of SCD and has been the primary focus of treatment, contemporary literature highlights the potential presence of developmental issues related to speech, language, neurocognitive, and auditory abilities that are often overlooked in SCD management.
Observations: This paper explores the spectrum of communication-related challenges that specifically affect children with SCD and fall within the scope of practice for speech-language pathologists (SLPs) and audiologists (AUDs).
Blood Adv
September 2025
Nationwide Children's Hospital Research Institute, Columbus, Ohio, United States.
Pediatr Infect Dis J
September 2025
Division of General Pediatrics, Department of Pediatrics, Gynecology and Obstetrics, Unit of Immunology, Vaccinology, and Rheumatology, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
Background And Aims: Sickle cell disease (SCD) patients are at a higher risk of pneumococcal invasive diseases. Vaccination is the central strategy for protecting these children, along with penicillin prophylaxis. However, it is unclear how often these children should be revaccinated with pneumococcal vaccines.
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