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Social determinants of health (SDoH) have been linked to a higher likelihood of experiencing mental health problems. This study aimed to investigate whether the accumulation of unfavorable SDoH is associated with depression symptom. Data was gathered from a representative population participating in the U.S. National Health and Nutrition Examination Survey spanning from 2005 to 2018. Self-reported SDoH were operationalized according to the criteria outlined in Healthy People 2030, with a cumulative measure of unfavorable SDoH calculated for analysis. The presence of depression symptom was identified using the Patient Health Questionnaire in a representative sample of 30,762 participants (49.2 % males) representing 1,392 million non-institutionalized U.S. adults, with 2,675 (8.7 %) participants showing depression symptom. Unfavorable SDoH were found to be significantly and independently associated with depression symptom. Individuals facing multiple unfavorable SDoHs were more likely to experience depression symptom (P for trend < 0.001). For instance, a positive association was observed in participants exposed to six or more unfavorable SDoHs with depression symptom (AOR = 3.537, 95 % CI: 1.781, 7.075, P-value < 0.001). The findings emphasize that the likelihood of developing depression symptom significantly increases when multiple SDoHs are present, compared to just a single SDoH.
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http://dx.doi.org/10.1016/j.psychres.2024.115894 | DOI Listing |
BMC Psychol
September 2025
Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON, M5S 1V4, Canada.
Background: Sexual and gender diverse adolescents and young adults (SGDAYA) experience mental health disparities, yet few empirical investigations into the long-term impact of affirmative treatments on their well-being exist.
Methods: This study explored the longitudinal effects of a brief affirmative cognitive-behavioral therapy (CBT) group intervention (AFFIRM) on the depression and anxiety of SGDAYA (N = 202), as well as how pre-treatment and mid-intervention change mechanisms contributed to their improved mental health. Participants' age ranged from 14 to 29 years old at baseline (M = 22.
J Relig Health
September 2025
U.O.C. di Oncologia Medica con Hospice, Dipartimento di Patologia Umana, DETEV, Azienda Ospedaliera Universitaria "G. Martino", Via Consolare Valeria, 1, 98124, Messina, Italy.
Spiritual support is increasingly recognized as a vital component of psychological care in palliative settings, yet its impact on emotional recovery is not fully established. The objective is to systematically review the benefits of integrating spiritual support into psychotherapy for improving emotional recovery in palliative care. A systematic search of PubMed, Web of Science, and Embase was conducted (September 1-10, 2024) with no date limits.
View Article and Find Full Text PDFInt J Clin Oncol
September 2025
Institute for Applied Research in Public Health, School of Public Health, Nantong University, Nantong, China.
Background: To evaluate the effects of cognitive-behavioral therapy (CBT) and mindfulness-based therapy (MBT), individually and in combination, on alleviating anxiety and depression, and improving quality of life (QoL) in breast cancer patients.
Methods: We searched PubMed and EMBASE for articles published up to April 6, 2025, using the keywords "randomized controlled trials (RCTs)", "cognitive-behavioral therapy", "mindfulness-based therapy", and "breast cancer". Pooled effects were expressed as standardized mean differences (SMDs) and 95% confidence intervals (CIs).
Eur J Pediatr
September 2025
Laboratory Physical Activity and Health, Center of Physical Education and Sport, State University of Londrina, Rodovia Celso Garcia Cid, PR-445, Km 380 - Campus Universitário, Londrina, Paraná, 86057-970, Brazil.
Unlabelled: The objective of this study is to analyze adherence to 24-h movement behavior recommendations (combined and isolated) with brain-derived neurotrophic factor (BDNF) in adolescents. For this cross-sectional study, 155 adolescents were recruited, of whom 141 participated; 118 with valid data were analyzed (64 girls, mean age 14.9 years).
View Article and Find Full Text PDFMol Psychiatry
September 2025
Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Background: Peripartum depression (PPD) is a form of major depressive disorder (MDD) that begins during the peripartum period and poses a significant mental health challenge affecting 10 to 29% of women.
Objective: This systematic review and multimodal activation likelihood estimation (ALE) meta-analysis explored the distinct structural, functional, and metabolic features of the PPD brain as compared to female non-peripartum MDD.
Methods: For this purpose, we conducted a comprehensive literature search in PubMed, Embase and PsycINFO databases to identify peer-reviewed original studies investigating the neural correlates associated with PPD or fMDD.