Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Treatment and follow-up strategies for silent gallbladder stones in patients before kidney transplantation (KT) remain unknown. Therefore, the authors aimed to elucidate the role of pre-KT cholecystectomy in preventing biliary and surgical complications.
Materials And Methods: This study retrospectively analyzed 2295 KT recipients and 3443 patients waiting for KT at a single tertiary center from January 2005 to July 2022. The primary outcomes were the incidences of biliary and postcholecystectomy complications in KT recipients. Firth's logistic regression model was used to assess the risk factors for biliary complications.
Results: Overall, 543 patients awaiting KT and 230 KT recipients were found to have biliary stones. Among the KT recipients, 16 (7%) underwent cholecystectomy before KT, while others chose to observe their biliary stones. Pre-KT cholecystectomy patients did not experience any biliary complications, and 20 (9.3%) patients who chose to observe their stones experienced complications. Those who underwent cholecystectomy before KT developed fewer postcholecystectomy complications (6.3%) compared with those who underwent cholecystectomy after KT (38.8%, P =0.042), including reduced occurrences of fatal postoperative complications based on the Clavien-Dindo classification. Multiple stones [odds ratio (OR), 3.09; 95% CI: 1.07-8.90; P =0.036), thickening of the gallbladder wall (OR, 5.39; 95% CI: 1.65-17.63; P =0.005), and gallstones >1 cm in size (OR 5.12, 95% CI: 1.92-13.69, P =0.001) were independent risk factors for biliary complications. Among patients awaiting KT, 23 (4.2%) underwent cholecystectomy during the follow-up, resulting in one postcholecystectomy complication.
Conclusion: Gallstone-related biliary complications following KT and subsequent cholecystectomy was associated with more serious complications and worse treatment outcomes. Therefore, when KT candidates had risk factor for biliary complications, pre-emptive cholecystectomy for asymptomatic cholecystolithiasis could be considered to reduce further surgical risk.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11175749 | PMC |
| http://dx.doi.org/10.1097/JS9.0000000000001394 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
When Carcinoembryonic Antigen Misleads: A Benign Cause of Tumor Marker Elevation.
Cureus
August 2025
Internal Medicine, Al Jahra Hospital, Al Jahra, KWT.
Carcinoembryonic antigen (CEA) is a commonly used tumor marker, primarily for the surveillance of colorectal and other gastrointestinal malignancies. However, its diagnostic specificity is limited, as CEA levels may be elevated in several benign conditions. This case report aims to highlight the potential diagnostic confusion and psychological distress caused by incidental CEA elevation in asymptomatic individuals when tested outside of an appropriate clinical context.
View Article and Find Full Text PDFLaparoscopic Subtotal Splenectomy in Pediatric Patients With Hematologic Disorders: A Case Series and Operative Technique.
Asian J Endosc Surg
September 2025
Department of Hematology and Oncology, Shizuoka Children's Hospital, Shizuoka, Japan.
Introduction: Total splenectomy in children increases the risk of overwhelming post-splenectomy infection (OPSI). Laparoscopic subtotal splenectomy (LSS) is a technique to preserve splenic function while managing disease burden in pediatric hematologic disorders.
Materials And Surgical Technique: Three children aged 4 to 9 years with juvenile myelomonocytic leukemia (JMML) or hereditary spherocytosis underwent LSS.
Acute Obstructive Jaundice Secondary to Surgical Clip Migration Into the Common Bile Duct 12 Years Following Laparoscopic Liver Resection: A Case Report.
Cureus
August 2025
Gastrointestinal and Pediatric Surgery, Tokyo Medical University, Tokyo, JPN.
Surgical clip migration to the common bile duct is a rare late complication, typically originating from clips placed at the cystic duct and most commonly reported after laparoscopic cholecystectomy. We present an exceptionally rare case of obstructive jaundice caused by clip migration from the liver dissection plane, rather than from the cystic duct, occurring 12 years after laparoscopic liver resection (LLR) and cholecystectomy and associated with chronic biliary inflammation. A 73-year-old man underwent LLR of segments 4a + 5 and cholecystectomy for hepatocellular carcinoma and was discharged on postoperative day 12 without any complications.
View Article and Find Full Text PDFOutcomes of concomitant laparoscopic sleeve gastrectomy and cholecystectomy.
J Gastrointest Surg
September 2025
Department of Surgery, University of Minnesota Medical School, Minneapolis, MN, United States. Electronic address:
Background: The development of cholelithiasis and its subsequent complications are a known risk after vertical sleeve gastrectomy (VSG) due to rapid weight loss. Although controversial, concomitant cholecystectomy (CCY) at the time of bariatric surgery has been proposed, with multiple studies investigating simultaneous CCY with Roux-en-Y gastric bypass. Despite VSG being the most commonly performed bariatric surgery in the United States (US) and globally, few studies have investigated the simultaneous VSG and CCY.
View Article and Find Full Text PDFThe robotic era: 11-year retrospective study of cholecystectomies at a veterans affairs hospital.
Surg Endosc
September 2025
Veterans Health Administration, Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
Background: Robotic surgery has been proposed as an approach to mitigate open surgery, which is associated with increased morbidity and worse outcomes when compared to minimally invasive cholecystectomies. The study objective was to determine the effect on conversion rates and outcomes following the adoption of robotic surgery for benign gallbladder disease in a high-risk population.
Methods: Patients ≥ 18 years of age who underwent cholecystectomy for benign gallbladder disease from January 1, 2013 to April 18, 2025 at a Veterans Affairs hospital were retrospectively identified.