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The effects of air pollution on physical health are well recognized, with many studies revealing air pollution's effects on vision disorder, yet no relationship has been established. Therefore, a meta-analysis was carried out in this study to investigate the connection between vision disorder and ambient particles (diameter ≤ 2.5 µm (PM), diameter ≤ 10 µm (PM)) and gaseous pollutants (nitrogen dioxide (NO), sulfur dioxide (SO), carbon monoxide (CO), Ozone (O)). Twelve relevant studies published by 26 February 2024 were identified in three databases. A pooled odds ratios (ORs) of 95% confidence intervals (CIs) were obtained using random-effects meta-analysis models. Meta-analysis results revealed that for every 10 µg/m increase in PM and NO exposure, a substantially higher incidence of vision disorder was observed (OR = 1.10; 95% CI: 1.01, 1.19; OR = 1.08, 95% CI: 1.00, 1.16). No significant correlation existed between exposure to PM, SO and CO and vision disorder. However, O exposure was negatively associated with vision disorder. In addition, subgroup analyses revealed that PM exposure was significantly correlated with the risk of glaucoma and age-related macular degeneration and that children and adolescents were more susceptible to NO and PM than adults. Overall, exposure to air pollutants, especially PM and NO, may increase the incidence of vision disorder.
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http://dx.doi.org/10.3390/toxics12030209 | DOI Listing |
J Vis
September 2025
Vrije Universiteit Amsterdam, Amsterdam Movement Sciences and Institute Brain and Behaviour Amsterdam (iBBA), Faculty of Behavioural and Movement Sciences, Amsterdam, Netherlands.
Eye tracking has the potential to be used as a meaningful measure of the consequences of vision impairment (VI), yet a comprehensive test battery is lacking. In this study, we sought to evaluate the feasibility and validity of a test battery of eye movements as a tool to measure visual performance in individuals with VI. A test battery including fixation stability, smooth pursuit, saccades, free viewing, and visual search was administered to 46 athletes with VI and 10 control participants.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
September 2025
Department of Ophthalmology, Edward S. Harkness Eye Institute, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, Columbia University, New York, New York, United States.
Purpose: To characterize a no b-wave (nob) mouse model of congenital stationary night blindness (CSNB) caused by a Grm6 variant that disrupts photoreceptor-to-bipolar cell signaling. Additionally, we aim to evaluate the efficacy of gene therapy in restoring visual function.
Methods: The nob mouse was generated through selective breeding to regenerate the nob phenotype.
Invest Ophthalmol Vis Sci
September 2025
The University of Leicester Ulverscroft Eye Unit, School of Psychology and Vision Sciences, University of Leicester, Leicester, United Kingdom.
Purpose: To define the genetic architecture of foveal morphology and explore its relevance to foveal hypoplasia (FH), a hallmark of developmental macular disorders.
Methods: We applied deep-learning algorithms to quantify foveal pit depth from central optical coherence tomography (OCT) B-scans in 61,269 UK Biobank participants. A genome-wide association study (GWAS) was conducted using REGENIE, adjusting for age, sex, height, and ancestry.
Tidsskr Nor Laegeforen
September 2025
Avdeling for bildediagnostikk, Sykehuset Østfold.
Background: Though rare, sphenoid sinusitis can cause abducens nerve palsy because of the anatomical proximity of the sphenoid sinus and the abducens nerve.
Case Presentation: A male patient in his late seventies presented with double vision and left abducens nerve palsy. Imaging revealed sinus opacifications later identified as due to Scedosporium apiospermum, a rare fungal pathogen.
Cureus
September 2025
Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, USA.
The spinal cord is an organ capable of sending and receiving a lot of biological and electrical information. It is not just a sending and receiving channel, but a living structure capable of autonomously processing the afferent and efferent notifications with which it comes into contact. The osteopathic neurological model includes the concept of facilitation of the spinal segment, that is, a reflex arc that is established in a spinal segment between two visceral and/or somatic structures, creating a loop of chronicity.
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