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http://dx.doi.org/10.2459/JCM.0000000000001613 | DOI Listing |
Int J Surg Case Rep
September 2025
Department of Internal Medicine, Pulmonology and Critical Care Unit, Bahir Dar University, Bahir Dar, Ethiopia.
Introduction And Importance: Lymphangioleiomyomatosis (LAM) is a rare disorder of unknown cause which mostly affects young females and involving multi organ system with primarily involving lung.
Presentation Of Case: A 35 year's old female Ethiopian known hypertension patient from Debre Tabor, Ethiopia, Africa; presented with progressively increasing cough with blood tingled sputum of 1-2 Arabic coffee cup per day, progressively increasing exertional shortness of breath and easy fatigability seven years back. Hypertensive and desaturate to level of 88 % at atmospheric air.
J Crit Care
September 2025
Universidade do Oeste de Santa Catarina, Campus de Joaçaba, Brazil; Hospital Universitário Santa Terezinha, Joaçaba, Brazil. Electronic address:
Background: Timely extubation is essential in ICU patients, yet traditional predictors such as the rapid shallow breathing index (RSBI) have limited accuracy. Diaphragm and lung ultrasound offer promising, non-invasive alternatives for assessing extubation readiness.
Methods: We conducted a prospective observational study nested within a randomized trial in a university ICU.
Hum Genet
September 2025
Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510620, Guangdong, China.
This study aims to assess the genetic burden of fetal congenital diaphragmatic hernia (CDH) and identify prenatal, perinatal, and postnatal predictors to improve early diagnosis, monitoring, and intervention. This study included 130 CDH fetuses who underwent invasive prenatal diagnosis, with fetal prognosis evaluated using imaging parameters such as observed-to-expected lung-to-head ratio (o/e LHR), observed-to-expected total lung volume (o/e TLV), and percent predicted lung volume (PPLV). Clinical outcomes included neonatal outcomes, extracorporeal membrane oxygenation (ECMO) requirement, and post-neonatal prognosis.
View Article and Find Full Text PDFInt J Cancer
September 2025
Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Immune checkpoint inhibitors (ICIs) are effective anti-tumor agents, but new immune-related side effects (irAEs) are emerging. This retrospective cohort study investigated 461 lung cancer patients treated with ICIs over 2 years, analyzing changes in pulmonary artery diameter (PAD), aortic diameter (AoD), and the pulmonary artery/aortic diameter (PAD/AoD) ratio through chest computed tomography (CT) at baseline, 3 months, 6 months, 1 year, and 2 years post-treatment. The PAD increased from 25.
View Article and Find Full Text PDFClin Lung Cancer
July 2025
Fox Chase Cancer Center, Temple Health, Philadelphia, PA. Electronic address:
Objective: This study examined brain metastases among patients with metastatic non-small cell lung cancer (mNSCLC), characterizing prevalence, use of brain imaging, and treatment patterns.
Methods: Surveillance, Epidemiology, and End Results (SEER) data linked to Medicare claims were used to examine the prevalence of brain imaging at diagnosis among Medicare beneficiaries with mNSCLC (2015-2019, inclusive of follow-up). Predictors of receipt of brain imaging and first-line systemic treatment were evaluated using logistic regression models.