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Background: Hikikomori (HK) is characterized by self-isolation and social refusal, being more likely also associated with affective disorders, including depression. This case-control study primarily aimed at identifying (if any) predominant affective temperaments are associated with HK in depressed versus not-depressed individuals. Secondary objectives comprise assessing which other psychopathological dimensions (e.g., boredom, anxiety) are associated with the HK specifier in depressed individuals.
Methods: From the larger SWATCH study, 687 Italian young people were screened for depression, as measured by 9 items-Patient Health Questionnaire (PHQ-9) and HK-like social withdrawal, through the Hikikomori Questionnaire-25 (HQ-25). All subjects were administered a brief-Temperament Evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-M), the 7 items-Generalized Anxiety Disorder (GAD-7) and the Multidimensional State Boredom Scale (MSBS).
Results: Males reported significantly higher scores at HQ-25 total score than females (p = 0.026). In the total sample, HK social withdrawal is positively predicted by MSBS low arousal, disengagement, depressive levels, depressive and irritable affective temperaments, while negatively by anxiety (F(6, 680) = 82.336, p < 0.001, R = 0.421). By selecting only depressed sample, HQ-25 is positively predicted by MSBS total score, low arousal and depressive affective temperament, while negatively by MSBS high arousal (F(4, 383) = 48.544, p < 0.001, R = 0.336). The logistic regression model found that the likelihood of developing depression with the HK specifier is significantly predicted by depressive and cyclothymic affective temperaments.
Conclusions: These preliminary findings could help in clinically characterizing the relationship between specific affective temperamental profiles among individuals with depression with/without HK specifier, in order to provide a more tailored and personalized therapeutic approach. Our Italian study should be extensively replicated in larger, longitudinal and multicentric pan-European studies, by specifically assessing the impact of these findings on depression clinical course, prognosis and treatment outcomes.
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http://dx.doi.org/10.1186/s12991-024-00496-z | DOI Listing |
J Affect Disord
September 2025
Institute for Development, Research, Advocacy, and Applied Care (IDRAAC), Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, Saint George University of Beirut Faculty of Medicine, Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, Saint George Hospital University Medi
Background: Temperament has been increasingly studied in relation to neurodevelopmental disorders, including Attention-Deficit/Hyperactivity Disorder (ADHD). This study examines the association between ADHD and affective temperament traits using the Temperament Scale of Memphis, Pisa, Paris, and San Diego (TEMPS-A) in a clinical outpatient sample in Beirut, Lebanon.
Methods: This cross-sectional study included 2564 psychiatric outpatients aged 15 or older who completed the TEMPS-A.
J Affect Disord
September 2025
Department of Psychology, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute (ACHRI), Calgary, AB, Canada; Department of Educational and Counselling Psychology, and Special Education (ECPS), University of British Columbia, BC, Canada.
Background: Perinatal depression has been linked to higher negative affectivity (NA) in children, though the strength of this association is variable. Infant sleep, a known protective factor, may moderate this relationship though this has not been tested.
Objective: To examine whether within-person changes in depressive symptoms across pregnancy and postpartum were linked to child NA, and whether infant sleep duration moderated these effects.
J Affect Disord
September 2025
Department of Psychiatry, University of North Carolina at Chapel Hill, United States of America.
Background: Perimenopausal onset depression (PO-MDD) is a common cause of distress and functional impairment, though efforts to describe its clinical symptomatology have been limited. We aimed to characterize affective and anxiety symptoms associated with PO-MDD, and to identify clinical correlates of distress, including anxiety, temperament and climacteric symptoms.
Methods: Baseline data from unmedicated women, ages 44-55, with PO-MDD (n = 49) and without PO-MDD (controls; n = 37) in the late-perimenopause (STRAW -1 criteria) recruited for two studies examining estrogen's effect on brain activation were included.
Pers Individ Dif
November 2025
Department of Psychology, The Pennsylvania State University, Pennsylvania, United States.
Taxonomic models of psychopathology and personality share striking similarities, but lines of research are often conducted independently. Integrating the two frameworks facilitates the inclusion of important constructs that are commonly overlooked in traditional models of psychopathology, but there is not yet consensus on the best joint factor structure (e.g.
View Article and Find Full Text PDFJ Affect Disord
September 2025
Department of Psychology, Brandenburg Medical School Theodor Fontane, Neuruppin, Germany.
Background: Bipolar disorders are amongst the most common, severe and chronic mental health conditions, often associated with unpredictable illness trajectories. Temperament, as a relatively stable however underutilized affective trait in clinical practice, has been proposed as a potential modifier of illness course in BD. The current study sought to classify and examine temperament as a predictive or distinguishing factor in the course of bipolar illness.
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