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Dynamically monitoring serotonin in real-time within target brain regions would significantly improve the diagnostic and therapeutic approaches to a variety of neurological and psychiatric disorders. Current systems for measuring serotonin lack immediacy and portability and are bulky and expensive. We present a new miniaturised device, named SmartFSCV, designed to monitor dynamic changes of serotonin using fast-scan cyclic voltammetry (FSCV). This device outputs a precision voltage potential between -3 to +3 V, and measures current between -1.5 to +1.5 μA with nano-ampere accuracy. The device can output modifiable arbitrary waveforms for various measurements and uses an N-shaped waveform at a scan-rate of 1000 V/s for sensing serotonin. Four experiments were conducted to validate SmartFSCV: static bench test, dynamic serotonin test and two artificial intelligence (AI) algorithm tests. These tests confirmed the ability of SmartFSCV to accurately sense and make informed decisions about the presence of serotonin using AI.
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http://dx.doi.org/10.1109/OJEMB.2024.3356177 | DOI Listing |
EBioMedicine
September 2025
Department of Radiology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, Shandong, 264000, PR China; Big Data and Artificial Intelligence Laboratory, Yantai Yuhuangding Hospital, Qingdao University, Yantai, Shandong, 264000, PR China. Electronic address:
J Particip Med
September 2025
Participatory Health, 20 Grasmere Ave, Fairfield, CT, 06824, United States, 1 (212) 280-1600.
JMIR Res Protoc
September 2025
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
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View Article and Find Full Text PDFJMIR Cancer
September 2025
iCARE Secure Data Environment & Digital Collaboration Space, NIHR Imperial Biomedical Research Centre, London, United Kingdom.
Background: Electronic health records (EHRs) are a cornerstone of modern health care delivery, but their current configuration often fragments information across systems, impeding timely and effective clinical decision-making. In gynecological oncology, where care involves complex, multidisciplinary coordination, these limitations can significantly impact the quality and efficiency of patient management. Few studies have examined how EHR systems support clinical decision-making from the perspective of end users.
View Article and Find Full Text PDFJ Med Internet Res
September 2025
School of Advertising, Marketing and Public Relations, Faculty of Business and Law, Queensland University of Technology, Brisbane, Australia.
Background: Labor shortages in health care pose significant challenges to sustaining high-quality care for people with intellectual disabilities. Social robots show promise in supporting both people with intellectual disabilities and their health care professionals; yet, few are fully developed and embedded in productive care environments. Implementation of such technologies is inherently complex, requiring careful examination of facilitators and barriers influencing sustained use.
View Article and Find Full Text PDF