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Article Abstract

root extracts were used for analysis by Gas Chromatography-Mass Spectrometry (GC-MS). The anticancer and antibacterial functions of extracts were also investigated. The dichloromethane extract of had the highest inhibitory effect against (18.00 ± 1.4 mm) at 100 mg/mL concentration. The lowest MIC was also achieved for treated with dichloromethane extract of (1.5 mg/mL). The minimum MBC (2 mg/mL) was observed for dichloromethane extract of root against . IC values of dichloromethane extracts of root (184.84 μg/mL) against HCT116 were lower than the ethyl acetate and butanol extracts (212.41 μg/mL and 223.93 μg/mL) at 72h. The butanol extract exhibited the most IC value on HEK293 (748.19 μg/mL). The biological properties of extracts may be assigned to the presence of numerous compounds detected in GC/MS analysis including n-Hexadecanoic acid, Linolenic acid, Palmitic acid, methyl ester, Stearic acid.

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http://dx.doi.org/10.1080/14786419.2024.2326993DOI Listing

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