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We experienced a case of papillary fibroelastoma of aortic valve, which had been located for preoperative 12 years without any symptom. We could assess tumor growth rate of 0.17 mm/year. Because of recent reports of recurrence, close follow-up should be continued.
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Ann Med Surg (Lond)
September 2025
Community Department, University of Bakht Alruda, Ad Duwaym, Sudan.
Rheumatic heart disease (RHD) and papillary fibroelastoma (PFE) are distinct cardiovascular disorders that can rarely occur together. RHD is a chronic condition caused by untreated streptococcal infections, primarily affecting the mitral valve and resulting in severe valvular damage. On the other hand, PFE is a benign heart tumor, usually affecting the aortic valve, and is typically asymptomatic, often discovered incidentally through imaging.
View Article and Find Full Text PDFCureus
July 2025
Department of Cardiology, Penn Cardiology, Vineland, USA.
Background Lambl's excrescences (LE) and cardiac papillary fibroelastomas (CPF) are valvular structures that have been associated with cryptogenic strokes, potentially acting as embolic sources or sites of thrombus formation. However, the management of LE and CPF - whether discovered incidentally or in the setting of cerebrovascular events (cardiovascular accident (CVA)/transient ischemic attack (TIA)) - remains poorly defined, with no randomized trials to guide treatment. Methods We conducted a retrospective case series at a single center from July 2018 to June 2024, identifying 10 patients with LE or CPF.
View Article and Find Full Text PDFJACC Case Rep
August 2025
Manchester Heart Centre, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Background: High-dose mediastinal radiotherapy can result in progressive valvular degeneration and secondary malignancy.
Case Summary: A 50-year-old woman with prior chest radiotherapy and stem cell transplantation for Hodgkin lymphoma presented with progressive exertional dyspnea. Transthoracic and transesophageal echocardiography revealed severe mitral regurgitation with mitral annular calcification and an incidental finding of a mobile 12 × 8 mm left atrial mass.
J Surg Case Rep
August 2025
Chulabhorn International College of Medicine, Thammasat University, Cooperative Learning Center-Piyachart, Pathum Thani 10120, Thailand.
Papillary fibroelastoma (PFE) is a rare, benign cardiac tumor usually arising from the heart valves, whereas non-valvular involvement is uncommon. We report herein a case of a 71-year-old Asian male who developed an ischemic stroke during hospitalization for gastrointestinal bleeding. A stroke workup led to the incidental detection of a cardiac mass in the left ventricular outflow tract, later confirmed as PFE following surgical excision without complications.
View Article and Find Full Text PDFDiagnostics (Basel)
August 2025
Department of Pathology, Faculty of Medicine, Akdeniz University, 07070 Antalya, Turkey.
Cardiac tumors are rare neoplasms with a wide spectrum of clinical presentations, ranging from asymptomatic cases to fatal outcomes. According to the 2021 thoracic tumor classification of the World Health Organization (WHO), papillary fibroelastoma (PFE) is the most common primary cardiac tumor. This study aimed to aggregate and examine data regarding the prevalence, clinical characteristics, and histological results of cardiac tumors.
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