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Background: The upright head roll test (UHRT) is a recently introduced diagnostic maneuver for lateral semicircular canal benign paroxysmal positional vertigo (LSC-BPPV).
Objective: This study aimed to evaluate the reliability and validity of the UHRT.
Methods: Two separate studies were conducted. Study 1 analyzed 827 results of videonystagmography (VNG) to assess UHRT reliability, and Study 2 analyzed 130 LSC-BPPV cases to evaluate UHRT validity.
Results: The inter-test reliability between UHRT and the supine head roll test (SHRT) showed substantial agreement (Cohen's kappa = 0.753) in direction-changing positional nystagmus (DCPN) and almost perfect agreement (Cohen's kappa = 0.836) in distinguishing the direction of DCPN. The validity assessment of UHRT showed high accuracy in diagnosing LSC-BPPV (80.0%) and in differentiating the variant types (74.6%). UHRT was highly accurate in diagnosing the canalolithiasis type in LSC-BPPV patients (Cohen's kappa = 0.835); however, it showed only moderate accuracy in diagnosing the cupulolithiasis type (Cohen's kappa = 0.415). The intensity of nystagmus in UHRT was relatively weaker than that in SHRT (P < 0.05).
Conclusion: UHRT is a reliable test for diagnosing LSC-BPPV and distinguishing subtypes. However, UHRT has a limitation in discriminating the affected side owing to a weaker intensity of nystagmus than SHRT.
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http://dx.doi.org/10.3233/VES-230127 | DOI Listing |
Front Neurol
August 2025
Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Introduction: External continuous perturbations using a motion platform have been developed by employing either sum-of-sines (SoS) or a pseudorandom ternary sequence (PRTS) of numbers to quantify body sway evoked in the medial-lateral (ML) or anterior-posterior (AP) directions, which ultimately helps understand the human postural control system. These stimuli have been provided via pitch tilts of the motion platform for evaluations of AP balance responses or roll tilts for ML balance responses. However, little is known about whether a healthy postural control system responds to 2-dimensional (2D) perturbations similarly when the perturbation stimuli are provided in semicircular canal coordinates (i.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Marianne Bernadotte Centrum, Department for Clinical Neuroscience, Karolinska Institutet; St Erik Eye Hospital.
The present protocol evaluates the relative impact of visual and vestibular inputs during roll plane rotations using optokinetic, vestibular, and combined visuovestibular stimulations. Subjects underwent isolated visual rotations, whole-body vestibular rotations in darkness, and visuovestibular stimulations combining static visual scenes with head rotations. Dynamic and static eye movement gains, absolute amplitudes, velocities, and accelerations were measured alongside perceptual responses.
View Article and Find Full Text PDFPLoS One
September 2025
University of Southampton, Electronics and Computer Science, Southampton, Hampshire, United Kingdom.
Social Anxiety Disorder (SAD) is a prevalent and debilitating condition characterized by heightened anxiety and avoidance behaviors in social situations. Despite the availability of treatment options, remission rates for SAD remain low, highlighting the need for more effective interventions. To support the development of more effective therapies, a better understanding of the psychophysiological mechanisms underlying SAD is needed.
View Article and Find Full Text PDFBioengineering (Basel)
July 2025
Musculoskeletal Oncology Division, Department of Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañón, Dr. Esquerdo 46, 28007 Madrid, Spain.
: Pelvic tumor resections demand high surgical precision to ensure clear margins while preserving function. Although patient-specific instruments (PSIs) improve osteotomy accuracy, positioning errors remain a limitation. This study evaluates the feasibility, accuracy, and usability of a novel dual-function augmented reality (AR) system for intraoperative guidance in PSI positioning and osteotomy execution using a head-mounted display (HMD).
View Article and Find Full Text PDFFront Neurol
August 2025
Departments of Ophthalmology, Neurology and Otorhinolaryngology, Head and Neck Surgery, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Passive motions can lead to conflicting combinations of visual and vestibular signals that can have a tremendous impact on our ability to navigate and comprehend the world. However, conflicting motion signals are also exploited for rehabilitation, adaptation training, and entertainment by creating functional illusions (VR, amusement parks). Low-frequency linear translations can induce "hilltop illusions," a perceptual phenomenon consisting in a reinterpretation of the inertial acceleration as tilt with respect to gravity.
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