Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11398889 | PMC |
| http://dx.doi.org/10.1152/japplphysiol.00761.2023 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Poor Accuracy of Blood Pressure Measurement Images Online: Implications for Public Health Education.
Hypertension
September 2025
School of Population Health, University of New South Wales, Sydney, Australia (A.E.S.).
Background: Blood pressure (BP) is a common clinical measurement, now increasingly done at home. Media websites often display images of BP measurement to represent clinical medicine, but many images deviate from guidelines, potentially creating misperceptions on how measurement should be performed. We evaluated the accuracy of BP measurement images online according to the 2023 International Consensus on Standardized Clinic BP Measurement.
View Article and Find Full Text PDFUnderstanding thromboembolus transport patterns in the brain for stroke in the presence of carotid artery stenosis.
PLoS Comput Biol
September 2025
Paul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, Colorado, United States of America.
Deciphering the source of an embolism is a common challenge encountered in stroke treatment. Carotid stenosis is a key source of embolic strokes. Carotid interventions can be indicated when a patient has greater than 50% stenosis in the carotid ipsilateral to the cerebral infarction, which is designated as the symptomatic carotid.
View Article and Find Full Text PDFTGFβ induces excessive pulmonary IL-6 secretion in cystic fibrosis via PI3K.
Am J Physiol Lung Cell Mol Physiol
September 2025
Division of Pulmonary Medicine, Cincinnati Children's Hospital, Cincinnati, OH.
Cystic Fibrosis (CF) is characterized by impaired mucociliary clearance and pulmonary infections. Accumulating evidence suggests that fundamentally abnormal inflammatory responses also contribute to CF pathology. TGFβ, a pleiotropic cytokine, is a modifier of CF lung disease; its mechanism of action in CF is unclear.
View Article and Find Full Text PDFDeletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice.
Am J Physiol Cell Physiol
September 2025
Institute of Pharmacology and Toxicology, Goethe University Frankfurt, Frankfurt, Germany.
The A20 binding inhibitor of nuclear factor-kappa B (NF-κB)-1 (ABIN-1) serves as a ubiquitin sensor and autophagy receptor, crucial for modulating inflammation and cell death. Our previous in vitro investigation identified the LC3-interacting region (LIR) motifs 1 and 2 of ABIN-1 as key mitophagy regulators. This study aimed to explore the in vivo biological significance of ABIN1-LIR domains using a novel CRISPR-engineered ABIN1-ΔLIR1/2 mouse model, which lacks both LIR motifs.
View Article and Find Full Text PDFIn Vitro Intraluminal Gel Infusion: An Advanced Approach for Microscopic Analysis of Human Resistance Arteries.
J Vis Exp
August 2025
Physiology Unit, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases.
Resistance arteries, which include small arteries and arterioles, play essential roles in regulating blood pressure and tissue perfusion. Dysfunction in these arteries can lead to various cardiovascular conditions such as hypertension, atherosclerosis, and heart failure, as well as neurovascular conditions. The examination of human resistance arteries is crucial for understanding cardiovascular disease mechanisms and developing targeted therapeutic strategies.
View Article and Find Full Text PDF