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Objective: Alcohol or drug impairment is a major risk factor for road traffic crashes, and studies on this issue are essential to provide evidence-based data for policymakers. In low- and middle-income countries (LMICs), such studies are often conducted in partnership with one or more organizations in high-income countries (HICs). The aim of this article is to provide recommendations for improving project planning and decision-making processes in epidemiological studies on alcohol, drug and traffic safety in LMICs involving HICs.
Methods: We searched Pubmed, Google Scholar, and Google Search for articles and reports in English about lessons learned when conducting collaborative research in LMIC as well as papers presenting recommendations for effective research collaboration with partners in LMICs.
Results: Based on the search results, we selected 200 papers for full text examination. Few were related to studies on the effect of alcohol or drug use on road traffic safety. However, several conclusions and recommendations from other studies were found to be relevant. We combined the findings with our own experience in a narrative review. We also present a checklist for risk and quality assessment.
Conclusions: Many papers presented similar recommendations, which included the importance of addressing local needs, ensuring adequate resources, local project ownership and leadership, establishing strong partnerships among all involved stakeholders, promoting shared decision-making and planning, and implementing strategies to translate research findings into policy, practice, and publications. It is also important to avoid HIC bias, which prioritizes the interests or perspectives of HICs over those of LMICs.
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http://dx.doi.org/10.1080/15389588.2024.2316720 | DOI Listing |
PLoS One
September 2025
University of Health and Allied Sciences, Volta Region-Ho, Ghana.
Introduction: The alarming rate of drug-resistant tuberculosis (DR-TB) globally is a threat to treatment success among positive tuberculosis (TB) cases. Studies aimed at determining the prevalence, trend of DR-TB and socio-demographic and clinical risk factors contributing to DR-TB in the four regions of Ghana are currently unknown. This study sought to determine the prevalence and trend of DR-TB, identify socio-demographic and clinical risk factors that influence DR-TB, and analyse the relationship between underweight and adverse drug reactions and treatment outcomes among DR-TB patients in four regions of Ghana.
View Article and Find Full Text PDFJ Addict Nurs
August 2025
Brandy Mechling, PhD, RN, PMHCNS-BC, FNAP, University of North Carolina Wilmington, Wilmington, NC.
In the United States, approximately 20 million individuals, age 12 and older, have a substance use disorder (SUD), with an average age of first-time use at 13 years old. Evidence has shown that many SUDs begin in adolescence, and involvement with the legal system can ensue. Adolescents with first-time drug and alcohol arrests can be referred to an Adolescent Intervention Program (AIP) as an alternative to jailtime from the juvenile court system.
View Article and Find Full Text PDFGen Physiol Biophys
September 2025
Faculty of Exact and Natural Sciences, I. Javakhishvili Tbilisi State University, Tbilisi, Georgia.
In this study, both pure and calcium-containing complex liposomes made from DPPC phospholipids were investigated using calorimetric and spectrophotometric methods. Liposomes were prepared using a new technology in both water and a 20% glycerol aqueous solution. Glycerol allows drug-containing DPPC liposomes to penetrate the dermis of the skin through the epidermis.
View Article and Find Full Text PDFJ Investig Med
September 2025
Unidad de Investigación Biomédica, Delegación Durango, Instituto Mexicano del Seguro Social, Durango, México.
It has been reported that DNA methylation in the epigenetic profile of the genes LEP and ADIPOQ is associated with obesity. To the best of our knowledge, there are no previous reports assessing the methylation of the LEP, LEPR, and ADIPOQ genes in subjects with metabolically healthy obesity (MHO). Therefore, the aim of this study was to determine the association between methylation of the LEP, LEPR, and ADIPOQ genes with the MHO phenotype.
View Article and Find Full Text PDFTurkiye Parazitol Derg
September 2025
Manisa Celal Bayar University Faculty of Medicine, Department of Medical Parasitology, Manisa, Türkiye.
Objective: () (common juniper) is a plant that has been used for medicinal purposes for centuries. This study aims to evaluate the antiparasitic effects of ethanol, methanol, chloroform, and water extracts of fruits against , , , and
Methods: The antiparasitic activities of fruit extracts prepared at room temperature using the shaking maceration method were tested against using the ring stage survival test, and against , , and using the broth microdilution method.
Results: The chloroform extract of fruits was found to be effective on , , , and parasites at concentrations of 15, 10, 30 and 30 µg/mL, respectively.