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Introduction: For patients with functional motor disorders of the lower limbs due to brain damage or accidental injury, restoring the ability to stand and walk plays an important role in clinical rehabilitation. Lower limb exoskeleton robots generally require patients to convert themselves to a standing position for use, while being a wearable device with limited movement distance.
Methods: This paper proposes a reconfigurable behavioral assistive robot that integrates the functions of an exoskeleton robot and an assistive standing wheelchair through a novel mechanism. The new mechanism is based on a four-bar linkage, and through simple and stable conformal transformations, the robot can switch between exoskeleton state, sit-to-stand support state, and wheelchair state. This enables the robot to achieve the functions of assisted walking, assisted standing up, supported standing and wheelchair mobility, respectively, thereby meeting the daily activity needs of sit-to-stand transitions and gait training. The configuration transformation module controls seamless switching between different configurations through an industrial computer. Experimental protocols have been developed for wearable testing of robotic prototypes not only for healthy subjects but also for simulated hemiplegic patients.
Results: The experimental results indicate that the gait tracking effect during robot-assisted walking is satisfactory, and there are no sudden speed changes during the assisted standing up process, providing smooth support to the wearer. Meanwhile, the activation of the main force-generating muscles of the legs and the plantar pressure decreases significantly in healthy subjects and simulated hemiplegic patients wearing the robot for assisted walking and assisted standing-up compared to the situation when the robot is not worn.
Discussion: These experimental findings demonstrate that the reconfigurable behavioral assistive robot prototype of this study is effective, reducing the muscular burden on the wearer during walking and standing up, and provide effective support for the subject's body. The experimental results objectively and comprehensively showcase the effectiveness and potential of the reconfigurable behavioral assistive robot in the realms of behavioral assistance and rehabilitation training.
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http://dx.doi.org/10.3389/fnbot.2024.1332721 | DOI Listing |
ACS Nano
September 2025
Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, United States.
Achieving high performance nanoscale photonic functionalities remains extraordinarily challenging when using naturally derived biomaterials. The ability to manipulate ultrathin films of structural proteins─combined with photolithographic control of their polymorphism─unlocks a compelling route toward engineering biopolymer-based photonic crystals with precisely defined photonic bandgaps and reconfigurable structural colors. In this work, we describe a robust, water-based fabrication process for silk/inorganic hybrid one-dimensional (1D) photonic crystals that overcomes many of the conventional difficulties in ensuring reproducibility, uniformity, and reliability at the nanoscale.
View Article and Find Full Text PDFACS Nano
September 2025
Frontiers Science Center for Transformative Molecules, State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.
Dynamic micro/nano-structured surfaces play pivotal roles in biological systems and engineering applications. Despite considerable progress has been made in fabricating precisely ordered architectures, achieving controlled motion in top-down fabricated structures remain a formidable challenge. Here, we introduce an advanced dynamic micron-nano optical platform featuring hierarchical microscale wrinkles integrated with ordered nanoscale arrays.
View Article and Find Full Text PDFEcol Evol
September 2025
Department of Hydrobiology, Institute of Biology University of Szczecin Szczecin Poland.
Physical habitat gradients in small rivers and streams profoundly influence aquatic community structure. These ecosystems are critical for biodiversity conservation, serving as refugia and nurseries for numerous species. Effective freshwater conservation necessitates tailored strategies addressing specific anthropogenic pressures and each habitat type's unique geomorphological and hydrological characteristics.
View Article and Find Full Text PDFFood Chem X
August 2025
Tianjin Institute of Industrial Biotechnology, Chinese Academy of Science, Tianjin 300308, China.
In this study, tannic acid (TA) was applied to remodel the structure of quercetin-loaded oat globulin fibrils (UF-Que), to form novel fibril-based composite hydrogels (UF-Que-TA) to encapsulate Que. The hydrogels were prepared by varying the [TA]/[UF] ratio to investigate the impact of TA on gelation behavior, microstructure, molecular interactions, and stability of Que. Physicochemical results indicated that the incorporation of TA significantly enhanced the gel strength and promoted non-covalent interactions including hydrogen bonding, hydrophobic interactions, and ionic interactions.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Division Macromolecular Chemistry, Leibniz Institute of Polymer Research Dresden, Hohe Strasse 6, Dresden, 01069, Germany.
Stimuli-responsive (multiphase) coacervates deserve significant attention as cell-like entities that can adapt to their environment and undergo morphological reconfiguration. In this study, a tandem-triggered transition system is presented that enables the transformation of single-phase coacervates into multiphase structures through the sequential application of two external stimuli: pH and salt concentration. A polyanion containing acid-labile amide bond is incorporated into the membrane-less coacervates.
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