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Unlabelled: The problem of antibiotic resistance is becoming increasingly serious worldwide due to uncontrolled prescription. Dentists are among the groups that prescribe the most antibiotics, often to delay urgent treatment. The purpose of the present study is to investigate the prescribing protocols adopted by dentists for prophylaxis and antibiotic therapy in major clinical surgical indications.
Methods: A ten-question survey was administered to a group of Italian dentists. The participants were asked about their preferences for antibiotic administration for the prevention of infective endocarditis, the administration of antibiotics to patients allergic to penicillin, the insertion of implants, and the extraction of third molars. The retrieved data were screened and analyzed.
Results: A total of 298 surveys were filled out. The most-prescribed antibiotic was amoxicillin or amoxicillin with clavulanic acid or macrolides for allergic patients. The administration of two grams of amoxicillin one hour before surgery was the most widely used prescriptive protocol for prophylaxis. International guidelines on antibiotic prophylaxis for infective endocarditis were only partially followed. The most heterogeneous results emerged for prophylaxis associated with dental implants or provided prior to surgical third-molar extraction.
Conclusions: The present study shows widespread antibiotic prescriptive heterogeneity among the sample of dentists analyzed, especially in conditions where international guidelines are lacking. An evidence-based consensus on prescriptive modalities in dentistry would be desirable in the near future.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10886335 | PMC |
http://dx.doi.org/10.3390/antibiotics13020189 | DOI Listing |
J Infect Public Health
September 2025
Department of Infectious Disease, Dijon Bourgogne University hospital, Dijon Cedex, France. Electronic address:
We report two cases of Elizabethkingia-related infective endocarditis, highlighting key risk factors such as prosthetic valve replacement. These cases underscore the need to consider endocarditis in the setting of persistent or recurrent bacteremia. Diagnosis proved challenging and required multiple imaging modalities, with positron emission tomography (PET) scan providing critical value when echocardiography was non-contributory.
View Article and Find Full Text PDFJACC Case Rep
September 2025
HonorHealth Thompson Peak Medical Center, Scottsdale, Arizona, USA.
Background: Surgical management is recommended for infective endocarditis (IE) when there is right heart failure due to severe tricuspid regurgitation, recurrent septic pulmonary emboli, persistent bacteremia, and large tricuspid valve vegetations (≥20 mm). However, sternotomy comes with strict eligibility limitations, including poor functional status, respiratory failure, and recent intravenous drug use.
Case Summary: A 55-year-old woman with a history of intravenous drug use was diagnosed with persistent bacteremia in the setting of tricuspid valve endocarditis.
JACC Case Rep
September 2025
Center for Structural Heart Disease, Henry Ford Health System, Detroit, Michigan, USA. Electronic address:
Case Summary: We present a case of a 31-year-old man with a history of aortic valve endocarditis and surgical aortic intervention. Computed tomography revealed a complex serpiginous fistula with 2 openings between the left ventricular outflow tract and the left atrium. Using 3-dimensional printing simulation for device fit testing and planning, the "mother-in-daughter" system, multimodality guidance with computed tomography angiography C-arm prediction, and 3-dimensional transesophageal echocardiogram guidance successfully guided an 18-mm Cribriform Amplatzer device deployed via a retrograde approach.
View Article and Find Full Text PDFJACC Case Rep
September 2025
Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Japan.
Background: Surgical treatment for infective endocarditis (IE) with severe thrombocytopenia is considered high risk and is often avoided.
Case Summary: A 67-year-old man with a history of 3 open-heart surgeries presented with fever and severe thrombocytopenia accompanied by a bleeding tendency. Blood cultures and transthoracic echocardiography confirmed IE of the aortic bioprosthetic valve caused by Candida parapsilosis.
Diagn Microbiol Infect Dis
September 2025
FMC Medical Center of Thailand, Nakhon Ratchasima, Thailand.
The recent article by Öberg et al. reports the creation and validation of novel MALDI-TOF MS libraries for Streptococcus bovis/Streptococcus equinus-complex (SBSEC) subspecies identification adapted to diagnostic culturing and extraction conditions. Their SBSECCMRS-BAE library demonstrated near-perfect identification performance, surpassing the Bruker MBT Compass and prior broth-based libraries.
View Article and Find Full Text PDF