Refining GFR estimation: a quest for the unobservable truth?

Kidney Int

Division of Nephrology, Department of Medicine, Houston Methodist Hospital and Houston Methodist Research Institute, Houston, Texas, USA. Electronic address:

Published: March 2024


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Article Abstract

Assessing glomerular filtration rate (GFR), which is central to evaluating kidney health, remains challenging. Measured GFR is not widely available and lacks standardization. Estimated GFR can be highly inaccurate for some patients and has limited applicability to many patient populations, such as those who are acutely ill. Recent metabolomic advances show promise for identifying new filtration markers that might enhance GFR estimation. Improving GFR assessment will require refinement in both GFR measurement and estimation methods.

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http://dx.doi.org/10.1016/j.kint.2023.12.004DOI Listing

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