Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cmi.2024.02.013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Treatment of adult T-cell leukemia/lymphoma: past, present, and future].
Rinsho Ketsueki
September 2025
Department of Hematology and Rheumatology, Kagoshima University.
Adult T-cell leukemia/lymphoma (ATL) is a T-cell malignancy caused by human T-cell leukemia virus type I (HTLV-1). Treatment strategies have been established by classification of ATL as aggressive (acute, lymphoma, and chronic ATL with any unfavorable prognostic factors) or indolent (smoldering and chronic ATL without any unfavorable prognostic factors). The standard of care (SOC) for aggressive ATL has been dose-intensified multi-agent chemotherapy.
View Article and Find Full Text PDFMaternal HIV Infection and Antiretroviral Therapy in Pregnancy: Implications for Vertical Transmission, Fetal Safety, and Long-Term Infant Outcomes.
Pathogens
August 2025
Department of Infectious Diseases, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540136 Targu Mures, Romania.
HIV mother-to-child transmission (MTCT) continues to pose a significant public health challenge, especially in regions with limited resources, although the worldwide distribution of antiretroviral therapy (ART) has drastically lowered the risk of vertical transmission to even below 1% in some regions. There are still uncertainties regarding the safety of some ART regimens during pregnancy and their longer-term effects on infants who are perinatally exposed to HIV but remain uninfected. This review explores current evidence regarding the interplay between maternal HIV infection, ART during pregnancy, and both maternal and pediatric outcomes.
View Article and Find Full Text PDFPhosphatidylethanolamine/PKA signal axis mediated human milk extracellular vesicles enhance adipose thermogenesis and lipolysis via mitochondrial remodeling.
Int J Obes (Lond)
August 2025
Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background/objectives: Emerging evidence suggests that extracellular vesicles (EVs) in breast milk may serve as an abundant source of candidates for regulating metabolism. Our study aims to identify phospholipids derived from human milk EVs (mEVs) that can benefit people with obesity.
Methods: Infant mice were either fed with formula milk or breastfed to investigate whether mEVs affect adipose tissue physiology in infants.
Pharmacokinetic Adaptations in Pregnancy: Implications for Optimizing Antiretroviral Therapy in HIV-Positive Women.
Pharmaceutics
July 2025
School of Medicine and Health Sciences, Universidad del Rosario, Bogota 111221, Colombia.
Pregnancy introduces significant physiological changes that alter the pharmacokinetics (PK) of antiretroviral therapy (ART), impacting its safety and efficacy in HIV-positive women. Optimizing ART during pregnancy is critical to maintaining maternal virological suppression and preventing mother-to-child transmission (MTCT) of HIV. This review evaluates the impact of pregnancy-induced PK changes on ART and proposes strategies for tailored regimens to improve outcomes.
View Article and Find Full Text PDFThe N2 During Preschool: Temporal Stability and a Test of Bidirectional Effects With Maternal Emotion Characteristics in a White, European-American Sample.
Child Dev
August 2025
Department of Psychological and Brain Sciences, Texas A&M University, College Station, Texas, USA.
Despite well-documented behavioral changes, the development of neuropsychological substrates underlying inhibitory control remains unknown, hindering understanding of this construct over time. Stability and change in N2, a neural correlate of inhibitory control, and its crosslagged, bidirectional associations with maternal emotion characteristics were examined in 121 preschoolers (59% female, predominantly White) between 2014 and 2017. N2 was stable from 3 to 5 years of age.
View Article and Find Full Text PDF