Milk to mucus: How B. fragilis colonizes the gut.

Cell Host Microbe

Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; Lifecourse Epidemiology of Adiposity and Diabetes Center, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address:

Published: February 2024


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Article Abstract

Human milk oligosaccharide (HMO) consumption by the infant microbiota is positively associated with immune health. In this issue of Cell Host & Microbe, Buzun et al. report a mechanism for HMO digestion by Bacteroides fragilis and demonstrate how the same pathway works on intestinal mucus to establish long-term gut residency.

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http://dx.doi.org/10.1016/j.chom.2024.01.007DOI Listing

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