Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Persistent left superior vena cava (PLSVC) is a rare venous anomaly, affecting 0.3-0.5% of the general population. Cardiac resynchronization therapy (CRT) implantation in patients with PLSVC is challenging due to a complex anatomy. Moreover, data on CRT implantation in this patient population is scarce. Our aim was to report a series of patients with PLSVC and CRT implantation focusing on challenges and pitfalls.
Methods: Electronic medical databases on patients with CRT implantation at the University Heart Centers in Zurich, Switzerland, and Lübeck, Germany, were screened for individuals with a PLSVC. Clinical and demographic characteristics as well as procedural data were reported in all patients.
Results: This study presents six cases with a median age of 66 years. CRT implantation was successful in five patients, leading to a reduced QRS duration and improved left ventricular ejection fraction. Atrial fibrillation, ischemic cardiomyopathy, valvular heart disease, and dilated cardiomyopathy were observed in this group as underlying conditions. Specialized tools, such as active fixation left ventricular leads, were utilized. One patient experienced major complications.
Conclusions: This case series shows that although challenging, conventional endovascular CRT implantation is feasible in PLSVC patients. Specialized tools for visualization and fixation may help. Our experiences highlight the importance of preprocedural evaluation of the anatomy and precise intervention planning.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522099 | PMC |
| http://dx.doi.org/10.1007/s10840-024-01761-7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cardiac resynchronization therapy in cancer patients with chemotherapy-induced cardiomyopathy: a mini review.
Heart Fail Rev
September 2025
Division of Provincial Cardiology, Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Chemotherapy-induced cardiomyopathy (CHIC) represents a growing clinical challenge due to the increasing use of cardiotoxic treatments. These therapies can lead to progressive myocardial dysfunction, ultimately resulting in heart failure. Cardiac resynchronization therapy (CRT) has been widely investigated in selected patients with chronic heart failure; however, those with CHIC remain underrepresented in CRT trials.
View Article and Find Full Text PDFComplications after complex device implantation: how important is implanter seniority?
Open Heart
September 2025
King's British Heart Foundation Centre of Research Excellence, School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, London, UK.
Background: The complication risk of procedures may be influenced by operator and institutional characteristics. Our aim was to assess whether supervising consultant seniority and operative volume, and hospital volume were associated with the risk of reintervention following complex device implantation.
Methods: A nationwide population-based study was performed using the National Institute for Cardiovascular Outcomes Research registry including all patients receiving their first transvenous implantable cardioverter defibrillator or cardiac resynchronisation therapy (CRT) implant in England over 5 years (April 2014-March 2019).
Clinical and echocardiographic outcomes of sync-atrioventricular versus nominal optimization in correlation with QRS narrowing among CRT patients.
BMC Cardiovasc Disord
August 2025
Department of Cardiology, Faculty of medicine, Aswan university, Aswan, Egypt.
Background: Cardiac resynchronization therapy (CRT) has been established as a key component in the management of patients with heart failure (HF) with reduced ejection fraction in addition to pharmacologic therapy. Several automatic algorithms have been developed to optimize the timing cycle settings in CRT, especially AV delay which was associated with improvement of the response to CRT. The present study aims to investigate whether the novel device-based SyncAV algorithm could elicit better synchrony and acute hemodynamic response.
View Article and Find Full Text PDFHead-to-Head Comparison of Single- Versus Dual-Chamber ICD Discriminators for Tachyarrhythmia Detection: A Single-Manufacturer, Remote Monitoring-Based Bicentric Study.
J Clin Med
August 2025
Department of Internal Medicine, Cardiology Center, Division of Electrophysiology, University of Szeged, 6725 Szeged, Hungary.
: Modern implantable cardioverter-defibrillators (ICDs) utilize single-chamber (SC) or dual-chamber (DC) discrimination algorithms to differentiate between tachyarrhythmias and minimize the risk of inappropriate therapies. While modern SC algorithms, especially those with morphology detection, are considered comparable to DC algorithms, the available data are limited. We aimed to compare the efficacy of SC and DC discrimination algorithms in malignant tachyarrhythmias.
View Article and Find Full Text PDFImplementation of lead V8 as a simple non-invasive tool to improve patient selection in CRT and guide LV lead placement.
Europace
August 2025
Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, The Netherlands.
Background And Aims: CRT improves outcomes in heart failure patients with electrical dyssynchrony. The QLV interval, a marker of delayed left ventricular (LV) activation, independently predicts CRT response. This study aimed to determine whether activation time measured in surface ECG lead V8 reflects postero-lateral LV delay by correlating with the QLV interval during biventricular (BiV) CRT implantation.
View Article and Find Full Text PDF