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We have demonstrated simultaneous detection of the polarization states and wavefront of light using a 7 × 7 array of angular variant micro-retarder-lenses. Manipulating the angular variant polarization with our optical element allows us to determine the two-dimensional distribution of polarization states. We have also proposed a calibration method for polarization measurements using our micro-retarder-lens array, allowing accurate detection of polarization states with an ellipticity of ± 0.01 and an azimuth of ± 1.0°. We made wavefront measurements using the micro-retarder-lens array, achieving a resolution of 25 nm. We conducted simultaneous detection of the polarization states and wavefront on four types of structured beam as samples. The results show that the two-dimensional distributions of the polarization states and wavefront for the four types of structured light are radially and azimuthally polarized beams, as well as left- and right-hand optical vortices. Our sensing technology has the potential to enhance our understanding of the nature of light in the fields of laser sciences, astrophysics, and even ophthalmology.
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http://dx.doi.org/10.1364/OE.509574 | DOI Listing |
J Am Chem Soc
September 2025
Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, Texas 75080-3021, United States.
The direct transformation of C-H bonds into C-C bonds via cross-dehydrogenative coupling (CDC) represents a powerful strategy in synthetic chemistry, enabling streamlined bond construction without the need for prefunctionalized substrates. While traditional CDC approaches rely on polar mechanisms and preactivation of one of the C-H partners, recent advances have introduced radical-based strategies that employ a hydrogen atom transfer (HAT) approach to access carbon-centered radicals from unactivated substrates. Herein, we report a nickel-catalyzed CDC reaction between aldehydes and alkenes for the synthesis of skipped enones, leveraging aryl radicals as intermolecular HAT agents.
View Article and Find Full Text PDFCancer Lett
September 2025
State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Tianjian Laboratory of Advanced Biomedical Sciences, Department of Radiology, Department of Clinical Research and Translational Medicine, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou,
The tumor microenvironment (TME) plays a pivotal role in cancer progression, though the molecular regulators governing its immunosuppressive properties remain incompletely characterized. In this study, we identify Makorin-2 (MKRN2) as a novel modulator of TME remodeling through integrated analyses of genetically engineered mouse models and human clinical data. Utilizing MKRN2 knockout mice, we observed significantly accelerated tumor growth compared to wild-type control, which was associated with profound alterations in immune cell composition, especially M2 macrophages.
View Article and Find Full Text PDFJ Phys Condens Matter
September 2025
Department of Physics, Tuskegee University, 1200 West Montgomery Road, 106 Chappie James, Tuskegee, Alabama, 36088-1920, UNITED STATES.
Spin qubit defects in two-dimensional materials have a number of advantages over those in three-dimensional hosts including simpler technologies for the defect creation and control, as well as qubit accessibility. In this work, we select the VBCB defect in the hexagonal boron nitride (hBN) as a possible optically controllable spin qubit and explain its triplet ground state and neutrality. In this defect a boron vacancy is combined with a carbon dopant substituting the closest boron atom to the vacancy.
View Article and Find Full Text PDFInt Immunopharmacol
September 2025
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, China-Singapore Belt and Road Joint Laboratory on Infection Research and Drug Development, National Medical Center for Infectious Diseases, Collaborative Innovation Cen
Macrophages play crucial roles in the progression of liver diseases. Increasing studies have shown that mesenchymal stem cells (MSCs) and their extracellular vesicles (MSC-EVs) could reshape the liver immune microenvironment by regulating the function and phenotype of macrophages, thereby exerting a therapeutic effect on liver diseases. Mitochondria, apart from being the central hub of energy metabolism, also finely regulate macrophage-mediated innate immune responses by modulating reactive oxygen species levels, cell polarization, and cell death.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
State Key Laboratory of Chemistry for NBC Hazards Protection, College of Chemistry, Fuzhou University, Fuzhou 350116, P. R. China.
The activation of methane and other gaseous hydrocarbons at low temperature remains a substantial challenge for the chemistry community. Here, we report an anaerobic photosystem based on crystalline borocarbonitride (BCN) supported Fe-O nanoclusters, which can selectively functionalize C-H bonds of methane, ethane, and higher alkanes to value-added organic chemicals at 12 °C. Scanning transmission electron microscopy and X-ray absorption spectroscopy corroborated the ultrafine FeOOH and FeO species in Fe-O clusters, which enhanced the interfacial charge transfer/separation of BCN as well as the chemisorption of methane.
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