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http://dx.doi.org/10.3390/cancers16020277 | DOI Listing |
Nat Med
July 2025
The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Polygenic scores (PGSs) for body mass index (BMI) may guide early prevention and targeted treatment of obesity. Using genetic data from up to 5.1 million people (4.
View Article and Find Full Text PDFNat Commun
July 2025
Center for Federated Learning in Medicine, Indiana University, Indianapolis, IN, USA.
Computational competitions are the standard for benchmarking medical image analysis algorithms, but they typically use small curated test datasets acquired at a few centers, leaving a gap to the reality of diverse multicentric patient data. To this end, the Federated Tumor Segmentation (FeTS) Challenge represents the paradigm for real-world algorithmic performance evaluation. The FeTS challenge is a competition to benchmark (i) federated learning aggregation algorithms and (ii) state-of-the-art segmentation algorithms, across multiple international sites.
View Article and Find Full Text PDFCirculation
April 2025
Division of Cardiology, University of Colorado School of Medicine, Aurora (G.G.S.).
JAAD Int
April 2025
Department of Dermatology, University of Lübeck, Lübeck, Germany.
Background: Prospective studies identifying immunological parameters that can predict clinical relapse in pemphigus are scarce.
Objective: To periodically assess immunological parameters in patients with pemphigus vulgaris and foliaceous in remission to understand immunological events preceding clinical relapse.
Methods: A total of 105 patients were included.
Background: There is low-certainty evidence on the impact of extended pharmacological prophylaxis on venous thromboembolism-associated morbidity and mortality. The aim of this study was to determine the efficacy and safety of extended prophylaxis after major abdominopelvic surgery for the prevention of clinically relevant venous thromboembolism after hospital discharge.
Methods: CArdiovaSCulAr outcomes after major abDominal surgEry (CASCADE) was a prospective, international, cohort study into which consecutive adult patients undergoing major abdominopelvic surgery were enrolled (January-May 2022).