Multiomics Reveals Mechanisms of Inhibiting Pathogenic Fungi in .

Endophytic fungi can benefit the host plant and increase the plant resistance. Now, there is no in-depth study of how () is enhancing the ability of inhibiting pathogenic fungi in (). In this study, the fungal community and metabolites associated with endophyte-infected (EI) and endophyte-free (EF) were compared by multiomics. The fungal community indicated that there was more , less phylum Ascomycota, and less genera , , and in the EI group. As metabolic biomarkers, the levels of swainsonine and apigenin-7-O-glucoside-4-O-rutinoside were significantly increased in the EI group. Through in vitro validation experiments, swainsonine and apigenin-7-O-glucoside-4-O-rutinoside can dramatically suppress the growth of pathogenic fungi and by increasing the level of oxidative stress. This work suggested that containing could increase the resistance to fungal diseases by markedly enhancing the content of metabolites inhibiting pathogenic fungi.