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Purpose: Urologic chronic pelvic pain syndrome (UCPPS), which encompasses interstitial cystitis/bladder pain syndrome in women and men and chronic prostatitis/chronic pelvic pain syndrome in men, is a common, often disabling urological disorder that is neither well understood nor satisfactorily treated with medical treatments. The past 25 years have seen the development and validation of a number of behavioral pain treatments, of which cognitive behavioral therapy (CBT) is arguably the most effective. CBT combines strategies of behavior therapy, which teaches patients more effective ways of behaving, and cognitive therapy, which focuses on correcting faulty thinking patterns. As a skills-based treatment, CBT emphasizes "unlearning" maladaptive behaviors and thoughts, and replacing them with more adaptive ones that support symptom self-management.
Materials And Methods: This review describes the rationale, technical procedures, and empirical basis of CBT.
Results: While evidence supports CBT for treatment-refractory chronic pain disorders, there is limited understanding of why or how CBT might work, for whom it is most beneficial, or the specific UCPPS symptoms (eg, pain, urinary symptoms) it effectively targets. This is the focus of EPPIC (Easing Pelvic Pain Interventions Clinical Research Program), a landmark NIH trial examining the efficacy of low-intensity, home-based CBT for UCPPS relative to a nonspecific comparator featuring self-care recommendations of AUA guidelines.
Conclusions: Systematic efforts to increase both the efficiency of CBT and the way it is delivered (eg, home-based treatments) are critical to scaling up CBT, optimizing its therapeutic potential, and reducing the public health burden of UCPPS.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10939861 | PMC |
http://dx.doi.org/10.1097/JU.0000000000003847 | DOI Listing |
Am J Case Rep
September 2025
Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; State Key Laboratory for Digestive Health; National Clinical Research Center for Digestive Diseases, Beijing, China.
BACKGROUND Non-traumatic bladder rupture, a rare yet potentially life-threatening condition, can stem from diverse factors such as malignancies, bladder inflammation, or bladder diverticulum rupture. Pelvic radiotherapy, in extremely rare instances, can lead to radiation cystitis and subsequent bladder fistula formation. Patients with such conditions often present with abdominal pain, hematuria, oliguria, and urinary ascites.
View Article and Find Full Text PDFArch Gynecol Obstet
September 2025
Faculty of Medicine, University of Lille, 59000, Lille, France.
Purpose: Endometriosis is a chronic, hormone-dependent disease affecting up to 10% of women of reproductive age, often associated with chronic pelvic pain (CPP). Neuropathic pain has been increasingly recognized as a significant component in a subset of patients with CPP related to endometriosis. The study objective was to assess the prevalence of neuropathic-like pain in women with deep endometriosis (DE) and CPP, and to analyze its influence on pain perception and quality of life.
View Article and Find Full Text PDFJ Surg Case Rep
September 2025
Department of Pathology, Tishreen University Hospital, Lattakia, Syria.
Endometriosis is a chronic gynecological condition characterized by the presence of endometrial-like tissue outside the uterine cavity. Although commonly associated with pelvic pain and infertility, its incidental discovery during a cesarean section is rare. To our knowledge, we report the first documented case of decidualized endometriosis identified on the anterior peritoneum during an emergency cesarean section in a 28-year-old woman with only one previous cesarean delivery and no prior symptoms.
View Article and Find Full Text PDFCureus
August 2025
Department of Neurosurgery, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, BGR.
This report presents the case of a 36-year-old man complaining of chronic low back pain and numbness along the posterolateral surface of the right leg. Magnetic resonance imaging (MRI) revealed a disc degeneration and protrusion at the L-S level and an extensive fluid-equivalent formation with a craniocaudal dimension of 8 cm at the S-S level. Initially, due to the minimal clinical complaints, the cyst was considered asymptomatic.
View Article and Find Full Text PDFJ Int Med Res
September 2025
Obstetrics and Gynecology Department, Wuhan University Zhongnan Hospital, China.
ObjectiveThis study aimed to evaluate the efficacy and safety of hyperthermic intraperitoneal intraoperative chemotherapy (HIPEC) in patients with advanced ovarian cancer.MethodsA total of 200 patients with advanced ovarian cancer were enrolled in this retrospective study and randomly allocated to two groups (research registry number: 11353). On the first day after abdominal closure, routine treatment was performed in the non-HIPEC group, whereas HIPEC was performed in the HIPEC group.
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