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The goal of this study was to examine the general public's level of accuracy and confidence in knowledge of chronic traumatic encephalopathy (CTE), as well as information sources. This study also explored how these factors affected comfort in allowing children to play a high-contact sport. This study utilized online surveys and included 529 participants. Overall, CTE knowledge accuracy was 48.02% (standard deviation = 0.23). Inaccuracies regarding the etiology and diagnosis of CTE were most common, whereas the symptoms and lack of treatments for CTE were more widely known. Despite overall low CTE knowledge accuracy, CTE knowledge confidence was positively correlated with comfort in allowing children to play a high-contact sport (r = 0.199, P ≤ 0.001). Participants identified television/movies followed by web sites and social media as the most utilized CTE information sources. These results further support the need for clinicians and researchers to address misconceptions about CTE.
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http://dx.doi.org/10.1249/JSR.0000000000001131 | DOI Listing |
Int J Mol Sci
July 2025
Department of Neurological Surgery, Northwestern Medicine, 676 N St Clair Street, Suite 2210, Chicago, IL 60611, USA.
Traumatic brain injury (TBI) initiates a complex cascade of pathophysiological events that have far-reaching consequences beyond the initial injury. This review examines the current state of the literature on the mechanisms underlying neurotrauma and neuroinflammation, with particular emphasis on the molecular cross-talk between these disparate pathways that ultimately precipitates the development of chronic traumatic encephalopathy (CTE). We integrate this mechanistic knowledge with potential diagnostic biomarkers, such as glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and advances in neuroimaging and machine learning-based predictive tools.
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August 2025
Cork University Hospital (CUH), Clinical Director of Emergency and Acute Care at CUH, Cork, Ireland.
Background: Sports related concussions are common in rugby. There is increasing awareness that repeated concussion may contribute to long-term neurological complications, including chronic traumatic encephalopathy (CTE).
Objectives: To evaluate concussion knowledge (CK), concussion attitude (CA) and Chronic Traumatic Encephalopathy related knowledge (CTE-K) amongst non-professional rugby players' in Ireland.
Br J Radiol
September 2025
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Objective: To develop and validate a novel CT enterography (CTE)-based radiomics nomogram for predicting disease activity in Crohn's disease (CD).
Methods: The CTE images and clinical data of 133 CD patients were retrospectively collected. The CTE-based radiomics features were extracted and screened by t-test and least absolute shrinkage and selection operator regression algorithm.
NPJ Digit Med
May 2025
College of Health Sciences, University of Alberta, Edmonton, AB, Canada.
Imaging is crucial to assess disease extent, activity, and outcomes in inflammatory bowel disease (IBD). Artificial intelligence (AI) image interpretation requires automated exploitation of studies at scale as an initial step. Here we evaluate natural language processing to classify Crohn's disease (CD) on CTE.
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