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http://dx.doi.org/10.1001/jamaoncol.2023.6060 | DOI Listing |
Cureus
August 2025
Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, USA.
While World Health Organization (WHO) grade I meningiomas are typically slow growing and associated with favorable prognoses, a subset may exhibit unexpectedly aggressive behavior and resistance to conventional treatment approaches. Recurrent grade I meningiomas, in particular, are associated with a poorer prognosis despite their benign histological classification, underscoring the need for advanced genomic and radiomic analyses to refine diagnostic accuracy. We present a case of a 52-year-old female with a grade I parafalcine meningioma initially deemed nonaggressive, but ultimately recurred multiple times over several years despite undergoing repeated craniotomies and several courses of radiosurgery.
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August 2025
Department of Oncology, University of Warmia and Mazury in Olsztyn, Olsztyn, POL.
Management of recurrent adenoid cystic carcinoma (ACC) in elderly patients remains challenging due to comorbidities, functional impairments, and anatomically complex tumor locations that complicate surgical access and increase operative risk. The ZAP-X Gyroscopic Radiosurgery System (ZAP Surgical Systems, Inc., San Carlos, CA, USA) offers a highly precise, non-invasive treatment modality, potentially suitable for salvage therapy in previously irradiated fields and in medically inoperable patients.
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August 2025
Department of Radiology, Aichi Medical University, Nagakute, JPN.
Background This study was conducted to examine the effects of moving the isocenter (IC) position from the lesion to the center of the brain on stereotactic radiosurgery (SRS) planning with volumetric-modulated arcs (VMA) using the High-Definition Dynamic Radiosurgery (HDRS) platform, a combination of the Agility multileaf collimator (MLC) (Elekta AB, Stockholm, Sweden) and the Monaco planning system (Elekta AB), for single brain metastases (BMs). Methodology The study subject included 36 clinical BMs with the gross tumor volume (GTV) ranging from 0.04 to 48.
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August 2025
Medicine, Fatima Jinnah Medical University, Lahore, PAK.
This study aimed to investigate the surgical management of cerebral arteriovenous malformations (AVMs) by analyzing clinical outcomes and complications in 600 patients (100%) who underwent surgery. The mean age of the cohort was 36.7 years (SD = 12.
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August 2025
Department of Radiology, Aichi Medical University, Nagakute, JPN.
Purpose This planning study aimed to clarify the significance of inverse planning with variable dose rate (VDR) and the segment shape optimization (SSO) in the quality and efficiency of dynamic conformal arcs (DCA) using the high-definition dynamic radiosurgery (HDRS) platform for stereotactic radiosurgery (SRS) of single brain metastases (BMs). Materials and methods Twenty clinical BMs were included, with the gross tumor volume (GTV) ranging from 0.33 cc to 48.
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