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To avoid the high rate of complications associated with the surgical management of adult spinal deformity, it is important to recognize and avoid three major pitfalls. The first is patient selection and determining which cases are appropriately indicated. The second is optimizing modifiable medical issues that can lead to a poor outcome, such as smoking, vitamin D deficiency, nutritional status, and poor bone quality. The third is optimizing surgical factors such as defining clinically appropriate, patient-specific target alignment goals as well as using techniques to avoid proximal junctional kyphosis and proximal junctional failure. It is important to describe these three key pitfalls that are commonly seen in the treatment of patients with adult spinal deformity and to describe methods to avoid them.
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Neurosurg Rev
September 2025
Department of Diagnostic and Interventional Neuroradiology, University Hospital Tübingen, Tübingen, Germany.
Purpose: To share our clinical experience with conservative management of isolated spinal arterial aneurysms (ISAs) and to identify clinical scenarios where conservative management may be appropriate, in the context of a literature review.
Methods: We performed a retrospective review of spinal angiograms from two German neuroradiology centers and conducted a systematic literature review of reported ISA cases. We analyzed demographics, clinical presentation, imaging findings, treatments, and outcomes.
J Neurosurg Sci
September 2025
Department of Neurological Surgery, University of Rochester Medical Center, Rochester, NY, USA.
Background: Symptomatic lumbar degenerative changes impact millions of patients per year. Recent technological advances have increased the usability of robot-assisted spinal fusions to treat this pathology. Although the safety profile of robotic systems appears favorable, the impact of robotics on surgical outcomes and efficiency remains unclear.
View Article and Find Full Text PDFJ Int Med Res
September 2025
Department of Orthopedics and Traumatology, Health Sciences University Fatih Sultan Mehmet Training and Research Hospital, Turkey.
ObjectiveTo determine the effectiveness of bilateral decompression combined with a unilateral transforaminal lumbar interbody fusion approach in centralizing a lordotic cage and preventing contralateral radiculopathy by ensuring equal foraminal elevation.MethodsThis is a retrospective cohort study based on clinical records and radiological data. Eighty-seven patients diagnosed with lumbar spinal stenosis at L3-S1 levels underwent bilateral decompression and transforaminal lumbar interbody fusion between 2017 and 2022.
View Article and Find Full Text PDFPain Rep
October 2025
Physiology, Pharmacology and Neuroscience, School of Life Sciences, The University of Nottingham, Nottingham, United Kingdom.
Introduction: The dorsal horn (DH) of the spinal cord is physiologically immature at birth. Spinal excitability increases and wide dynamic range (WDR) neurons in lamina V have lowered activation thresholds and larger receptive field sizes.
Objective: The DH is composed of 5 laminae containing diverse interneuronal populations yet our understanding of the physiology of the DH is based on behavioural studies or extrapolation of single cell WDR recordings to the whole network.
Cureus
September 2025
Rheumatology, University Hospitals Coventry & Warwickshire, Coventry, GBR.
Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition that may develop after fractures, surgery, or soft tissue trauma. It is characterized by pain disproportionate to the initial injury, often accompanied by sensory, motor, autonomic, and trophic changes. Despite extensive research, pathophysiology remains unclear, and treatment approaches are varied, with inconsistent supporting evidence.
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