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Concurrently to the recent development of percutaneous tracheostomy techniques in the intensive care unit (ICU), the amount of tracheostomized brain-injured patients has increased. Despites its advantages, tracheostomy may represent an obstacle to their orientation towards conventional hospitalization or rehabilitation services. To date, there is no recommendation for tracheostomy weaning outside of the ICU. We created a pluridisciplinary tracheostomy weaning protocol relying on standardized criteria but adapted to each patient's characteristics and that does not require instrumental assessment. It was tested in a prospective, single-centre, non-randomized cohort study. Inclusion criteria were age > 18 years, hospitalized for an acquired brain injury (ABI), tracheostomized during an ICU stay, and weaned from mechanical ventilation. The exclusion criterion was severe malnutrition. Decannulation failure was defined as recannulation within 96 h after decannulation. Thirty tracheostomized ABI patients from our neurosurgery department were successively and exhaustively included after ICU discharge. Twenty-six patients were decannulated (decannulation rate, 90%). None of them were recannulated (success rate, 100%). Two patients never reached the decannulation stage. Two patients died during the procedure. Mean tracheostomy weaning duration (inclusion to decannulation) was 7.6 (standard deviation [SD]: 4.6) days and mean total tracheostomy time (insertion to decannulation) was 42.5 (SD: 24.8) days. Our results demonstrate that our protocol might be able to determine without instrumental assessment which patient can be successfully decannulated. Therefore, it may be used safely outside ICU or a specialized unit. Moreover, our tracheostomy weaning duration is very short as compared to the current literature.
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http://dx.doi.org/10.1007/s00455-023-10641-7 | DOI Listing |
Pediatr Pulmonol
September 2025
Perinatal Institute, Division of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Objective: To wean respiratory support, preterm infants with severe respiratory failure are often administered systemic corticosteroids. We sought to evaluate if postnatal age or clinical characteristics predicted death or tracheostomy following systemic dexamethasone in evolving bronchopulmonary dysplasia.
Study Design: We performed a retrospective study of infants born at ≤ 30 weeks' gestational age cared for at a Level IV referral center from 2009 to 2019 who received a complete course of systemic dexamethasone beyond 4 weeks of age for the indication of preventing death and/or liberating from positive pressure ventilation.
Sao Paulo Med J
September 2025
Professor; Physician. Hospital Alemão Oswaldo Cruz, São Paulo (SP), Brazil.
Background: The coronavirus disease 2019 (COVID-19) pandemic has placed unprecedented strain on healthcare systems, particularly on critically ill patients requiring prolonged mechanical ventilation (MV). Percutaneous tracheostomy (PT) has emerged as a potential strategy to facilitate weaning, reduce intensive care unit (ICU) stay, and optimize resource use. However, the timing, safety, and outcomes of PT in COVID-19 patients remain debatable.
View Article and Find Full Text PDFCureus
July 2025
Division of Intensive Care, Department of Emergency and Disaster Medicine, Kashiwa Hospital, The Jikei University School of Medicine, Tokyo, JPN.
A 70-year-old woman with a history of malignant lymphoma (in remission) and systemic sclerosis required mechanical ventilation because of severe coronavirus disease 2019 pneumonia. Despite the administration of broad-spectrum antibiotics, antifungal agents, and corticosteroids, respiratory failure persisted, and a tracheostomy was performed on hospital day 17. Ventilator weaning remained difficult up to hospital day 30 and persistent detection of the severe acute respiratory syndrome coronavirus 2 antigen prompted initiation of remdesivir.
View Article and Find Full Text PDFCureus
August 2025
Cardiovascular Surgery, Hokkaido Prefectural Kitami Hospital, Kitami, JPN.
We report a case of totally endoscopic mitral valve repair for severe mitral regurgitation (MR) due to Barlow's disease in a 55-year-old man with severe pulmonary dysfunction following coronavirus disease 2019 (COVID-19) pneumonia. He had developed severe COVID-19 one month earlier, requiring veno-venous extracorporeal membrane oxygenation (V-V ECMO). Although successfully weaned from ECMO, the patient continued to experience persistent fever and was referred to our department for suspected acute MR.
View Article and Find Full Text PDFActa Anaesthesiol Scand
September 2025
Division of Critical Care, Department of Medicine, Western University, London Health Sciences Center, London, Ontario, Canada.
Background: Patients requiring invasive mechanical ventilation (MV) encounter significant morbidity and mortality in the ICU. High-flow tracheal oxygen (HFTO) is used in tracheostomized patients to facilitate MV weaning. However, its impact on clinical outcomes is unclear.
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