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Ticks are second only to mosquitoes in their importance as vectors of disease agents; however, tick-borne diseases (TBDs) account for the majority of all vector-borne disease cases in the United States (approximately 76.5%), according to Centers for Disease Control and Prevention reports. Newly discovered tick species and their associated disease-causing pathogens, and anthropogenic and demographic factors also contribute to the emergence and re-emergence of TBDs. Thus, incorporating different tick control approaches based on a thorough knowledge of tick biology has great potential to prevent and eliminate TBDs in the future. Here we demonstrate that replication of a transovarially transmitted rickettsial endosymbiont depends on the tick's autophagy machinery but not on apoptosis. Our findings improve our understanding of the role of symbionts in tick biology and the potential to discover tick control approaches to prevent or manage TBDs.
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http://dx.doi.org/10.1128/spectrum.01086-23 | DOI Listing |
Am J Trop Med Hyg
September 2025
Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Haemaphysalis leporispalustris (the rabbit tick) is one of the most broadly distributed hard tick species in the Americas. In 2018, investigators amplified DNA from a spotted fever group Rickettsia (SFGR) species found in host-seeking larvae and nymphs of H. leporispalustris collected in northern California and proposed the name Candidatus "Rickettsia lanei" using results obtained via multilocus sequence typing.
View Article and Find Full Text PDFExp Parasitol
September 2025
Department of Veterinary Parasitology, College of Veterinary Science, Guru Angad Dev Veterinary & Animal Sciences University, Ludhiana, India. Electronic address:
Rhipicephalus microplus, an important ixodid tick species, poses significant economic and health challenges to the livestock directly by impairing animal productivity and serving as a vector for various pathogens. Although tick control strategies broadly integrate synthetic acaricides and environmental management, the emergence of acaricide resistance undermines these efforts thereby, necessitating alternative approaches. This study evaluated the acaricidal efficacy of six essential oil components (EOCs) such as cedrol, cinnamaldehyde, citral, eugenol, limonene and menthol against deltamethrin and ivermectin resistant R.
View Article and Find Full Text PDFJ Travel Med
September 2025
Virology and Pathogenesis Group, Public Health Microbiology, UK Health Security Agency, Porton Down, UK.
Our UK field investigations of tick-borne encephalitis virus were abruptly interrupted by a bed bug infestation in our short-term rental accommodation. Subsequent weeks were spent decontaminating belongings and monitoring our homes. As global bed bug infestations rise, increased awareness of prevention and control strategies is crucial for both travellers and accommodation providers.
View Article and Find Full Text PDFVector Borne Zoonotic Dis
September 2025
Key Laboratory of Forensic Medicine, Institute of Medical Sciences, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi City, China.
spp. are widespread in ticks. , the agents of Q fever, is vectored by ticks and is well known for its veterinary and medical importance.
View Article and Find Full Text PDFJ Med Entomol
September 2025
Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.
The United States Centers for Disease Control and Prevention introduced the National Tick Surveillance Program in 2018 to better define areas of acarologic risk in response to the increasing burden of blacklegged tick (Ixodes scapularis, Acari: Ixodidae)-associated infections. The program coordinates surveillance efforts conducted by state and local public health programs and collates acarological data in the ArboNET Tick Module national database. Among the metrics collected, the density of infected host-seeking nymphs (DIN) is believed to be most closely correlated with the reported occurrence of tick-borne diseases.
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