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Calcium gluconate solutions are an essential part of the intensive care medication armamentarium. Calcium-related extravasations are not an infrequent occurrence. However, occult extravasation presenting solely as an isolated mass lesion with no preceding cutaneous manifestation is rare. Calcinosis cutis is an extraosseous collection of calcium deposits in the skin and subcutaneous tissues. Multiple etiopathogenetic factors play a role in its manifestations. We illustrate a case of a seven-week-old infant diagnosed with pseudo-hypoaldosteronism with a mysterious swelling on the left leg during the third week of hospitalization, which was attributed to occult iatrogenic calcinosis cutis.
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http://dx.doi.org/10.7759/cureus.47579 | DOI Listing |
Arthritis Rheumatol
September 2025
Department of Nephrology and Rheumatology, Kanazawa University Hospital, Kanazawa, Japan.
J Educ Teach Emerg Med
July 2025
University of Texas Southwestern Medical Center, Department of Emergency Medicine, Dallas TX.
Unlabelled: Calcinosis cutis is a condition in which calcium-phosphate salt deposits are formed in cutaneous and subcutaneous tissue. A subtype, metastatic calcinosis cutis, can occur in patients with disorders that cause hypercalcemia or hyperphosphatemia such as end stage renal disease. We present a case of a 67-year-old man with end-stage renal disease (ESRD) on dialysis who presented to the emergency department with a draining left elbow wound.
View Article and Find Full Text PDFClin Exp Dermatol
July 2025
Dermatology Department, King's College Hospital NHS Foundation Trust, London, UK.
Vet Dermatol
July 2025
San Marco Veterinary Clinic and Laboratory, Veggiano, Italy.
This report presents the clinical features, clinicopathological changes, computed tomography images and response-to-treatment of a dog with calcium-laden subcutaneous fluid collections, resembling a rare form of calcinosis in humans termed 'milk of calcium'.
View Article and Find Full Text PDFSkin Health Dis
June 2025
Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Trisomy 18 is the second most common autosomal trisomy, associated with high mortality, with only 5-10% of affected individuals surviving beyond the first year of life. Consequently, comorbidities in long-term survivors are rarely reported. We describe the case of a 6-year-old East Asian girl with trisomy 18 who presented with calcinosis cutis.
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