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Introduction: The aim of this study was to assess the prevalence of external cervical resorption (ECR) and characterize the cases of ECR using cone beam computed tomography (CBCT).
Methods: High-resolution CBCT scans of 6216 patients (2280 males and 3936 females), consecutively acquired during the period July 2021 to March 2022, were analyzed. Identified cases of ECR were characterized by 3 evaluators regarding lesion height, circumferential spread, portal of entry proximity to root canal, stage, location, and width.
Results: In a total of 38 patients and 40 teeth, ECR cases demonstrated an incidence of 0.61%. The median age of the patients was 39 years. Prevalence of ERC was 0.78% among males and 0.50% among females. The most affected teeth were the maxillary incisors and canines. The most frequent characteristics of the lesion were: extension up to the cervical third (47.5%), more than 270° circumferential spread (42.55%), probable pulpal involvement (57.5%), progressive stage (65%), supracrestal (52.1%) and mesial (34.7%) localization of >1 mm in size (52.1%) portals of entry. Cases with greater longitudinal involvement also showed greater circumferential progression (P = .008). There was no association between portal of entry location and bone crest or ECR reparative phase (P = .42). Inter-rater agreement ranged from good to very good. No association between portal of entry and ECR progression was observed.
Conclusions: ECR showed low prevalence in the Brazilian population, affecting mostly anterior maxillary teeth of patients within a wide age range. CBCT allowed characterization of ECR lesions with good interobserver agreement.
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http://dx.doi.org/10.1016/j.joen.2023.11.003 | DOI Listing |
Eur J Cancer
September 2025
Medical Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Milan, Italy.
Aim Of The Study: The aim of the study is to describe clinical features, treatment approach and outcomes of recurrent/metastatic (R/M) NPC in non-endemic areas MATERIALS AND METHODS: This observational, retrospective and multicenter study was conducted within 36 referral hospital in non-endemic areas including Europe, Jordan, Kuwait, Turkey and United States of America. All NPC patients diagnosed between 2004 and 2016 and with a minimum 12 months of follow-up were included. Data entry started in January 2018 and closed in December 2023.
View Article and Find Full Text PDFRev Esp Med Nucl Imagen Mol (Engl Ed)
August 2025
Servicio de Medicina Nuclear, Hospital Central de la Defensa "Gómez Ulla" CSVE, Madrid, Spain.
Acta Vet Scand
August 2025
Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Grønnegårdsvej 7, Frederiksberg C, DK-1870, Denmark.
Background: Antibiotic treatment of piglets after birth is commonly carried out due to concern for development of omphalitis leading to umbilical outpouchings and/or systemic infections. Among others, the portal of entry for bacterial infections includes the umbilical cord at birth. The aim was to characterise the histological and bacteriological pattern of manifestations in the umbilicus of piglets with omphalitis that died during the suckling period in a Danish herd.
View Article and Find Full Text PDFViruses
August 2025
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), 28049 Madrid, Spain.
CD9 protein belongs to a family of proteins called tetraspanins, so named for their four-transmembrane-spanning architectures. These proteins are located in domains in the plasmatic membrane, called tetraspanin-enriched microdomains (TEMs). Several proteases and cellular receptors for virus entry cluster into TEMs, suggesting that TEMs are preferred virus entry portals.
View Article and Find Full Text PDFAltern Ther Health Med
August 2025
Department of Epidemiology, ICMR-National Institute of Epidemiology, Chennai, Tamil Nadu, India.
Background: Research quality in Ayush systems of medicine is vital for evidence synthesis and decision-making. As Ayush gains global recognition, analyzing its trends and challenges is important for improving clinical outcomes. However, a comprehensive analysis of research publications is lacking.
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