Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
This study aimed to evaluate the efficacy of a novel jet dispenser (JD) for filling simulated straight and curved canals with calcium hydroxide (Ca(OH)) paste by comparing the level of intracanal medicament with traditional direct syringe delivery. The Ca(OH) paste was delivered into the canals using either a direct syringe with binding tip and unbinding tip or a JD. The analysis of the ratio of the canal filled area (RCFA) in the coronal, middle, and apical thirds was conducted using the Kruskal-Wallis and Mann-Whitney U tests (α = 0.05). The JD resulted in a significantly higher RCFA of 1.00 in the middle and apical thirds in both the straight and curved canals than the direct syringe method (p < 0.001). Voids were frequently observed in the direct syringe group, whereas JD showed no voids within the filled area. In the direct syringe groups, the apical area was more readily filled in both canal types when the tip was bound (p < 0.001). The JD was found to be more effective in filling the entire canal space than the binding and unbinding conditions of the direct injection method, particularly in the apical area.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636178 | PMC |
| http://dx.doi.org/10.1038/s41598-023-46683-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A handheld microfluidic manifold for massively multiplexed CRISPR-based nucleic acid detection.
bioRxiv
August 2025
Department of Molecular Biology, Princeton University, Princeton, New Jersey, 08544, USA.
Multiplexed methods for nucleic acid detection are immensely challenging to deploy outside of laboratory settings. Conversely, field-deployable methods are limited to low levels of multiplexing. During the COVID-19 pandemic, we developed Streamlined Highlighting of Infections to Navigate Epidemics (SHINE), a sensitive and deployable CRISPR-based technology for nucleic acid detection.
View Article and Find Full Text PDFFlexibly actuated pneumatic extrusion with in-situ monitoring for direct ink writing of heterogeneous and pressure-vulnerable materials.
Sci Rep
August 2025
Department of Mechanical Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand.
This study presents a novel piston-driven pneumatic extrusion system for direct ink writing (DIW), featuring flexible actuation and real-time monitoring of extrusion pressure. The design integrates the benefits of both pressure and feedrate control, achieving consistent linewidth while safeguarding pressure-sensitive materials such as cell-laden hydrogels. The system comprises a lightweight pneumatic syringe on the printhead and a stationary actuation unit, allowing efficient decoupling of motion and extrusion.
View Article and Find Full Text PDFWhich sucks more? Comparison of two novel direct-in-scope suction ureteroscopes to a conventional ureteroscope.
World J Urol
August 2025
Department of Urology, Loma Linda University Health, Loma Linda, CA, USA.
Introduction: Novel Direct-In-Scope-Suction ureteroscopes (DISS-U) have recently been introduced to facilitate removal of small stone fragments. The purpose of this study was to compare two novel DISS-U to a conventional ureteroscope to determine efficiency for suctioning fluid and stone dust at different deflection angles.
Methods: Three disposable ureteroscopes were evaluated, including two DISS-U with 5.
Investigating Zinc Migration from Rigid Needle Shield to Drug Formulation in Needle Tip of Pre-filled Syringe.
Pharm Res
August 2025
ANAXAM, Park Innovaare, Parkstrasse 1, CH-5234, Villigen, Switzerland.
Objective: This study investigates the underexplored mechanisms of needle clogging in pre-filled syringes (PFSs), focusing on zinc (Zn) ions, which have been reported to promote protein gelation and increase formulation viscosity. We present direct evidence of Zn migration from the rigid needle shield (RNS) into drug products, aiming to elucidate the migration pathways and the role of Zn in clogging.
Methods: Pre-filled syringes containing a therapeutic monoclonal antibody (mAb) were stored at 5°C and subjected to stress conditions at 40°C for up to six months.
A Low Protein Binding Electrospun Membrane Filter for Efficient Biological Media Sterilization.
ACS Omega
July 2025
Amrita School of Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Ponekkara, Kochi, Kerala 682024, India.
This study exploited the water repelling hydrophobic nature of polycaprolactone (PCL) fibers for efficient filtration of water-based fluids toward development of an affordable sterile membrane filter by the process of electrospinning. Electrospun (ES) nanosized fibrous membranes of different thicknesses presented high force at break and minimal elongation supported syringe filtration. The membrane hydrophobicity facilitated easy filtration of small volumes of biological fluids (∼1 mL) without any wetting media loss.
View Article and Find Full Text PDF