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BACKGROUND: Stroke is a medical emergency requiring timely intervention to optimize patient outcomes. The only treatments currently Food and Drug Administration approved for acute stroke are intravenous (IV) thrombolytics, which require obtaining specific medical history to be administered safely. This medical history may be overlooked in the prehospital setting or lost during patient handoff between emergency medical services (EMS) personnel and hospital staff, delaying treatment. We evaluated whether utilization of a "stroke alert sticker" by EMS to capture key information in the field would decrease door-to-needle (DTN) time. METHODS: Bright-orange "stroke alert stickers" were disseminated to our local EMS agency to be placed on all suspected stroke patients in the field prompting documentation of key elements needed for timely treatment decisions. The "stroke alert sticker" included time last known well, contact information, presenting symptoms, and relevant medications. We evaluated the impact of the "stroke alert sticker" on acute stroke metrics, including DTN time. RESULTS: The project included 220 consecutive stroke alert patients brought to our comprehensive stroke center by a single EMS agency from May 2021 through February 2022. Twenty-one patients were treated with an IV thrombolytic. Overall "stroke alert sticker" use compliance was 40%; for the subgroup of patients who were given an IV thrombolytic, the "stroke alert sticker" was used 60% of the time. In patients who received an IV thrombolytic, prehospital EMS notification was 100% with "stroke alert sticker" use, compared with 75% without (P = .13). In addition, with "stroke alert sticker" utilization, DTN time was reduced by 20 minutes (31 [11] minutes with sticker vs 51 [21] minutes without, P = .04). CONCLUSION: Utilization of the "stroke alert sticker" significantly improved DTN times compared with patients without the sticker. This evidence supports continued use of the "stroke alert sticker" to improve DTN times and patient outcomes.
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http://dx.doi.org/10.1097/JNN.0000000000000728 | DOI Listing |
Nurs Health Sci
September 2025
School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
This study used latent class analysis to explore the potential characteristics of stroke preparedness and the factors that influence it in middle-aged and older adults. A total of 845 middle-aged and older adults were recruited from 16 communities in Guangdong Province between July and August 2022. We identified four potential categories of stroke preparedness among middle-aged and older adults: recognition of stroke-emergency medical services (EMS) activation, low symptoms alertness-hospital avoidance, recognition of stroke-go to the hospital, and overlook arm weakness-go to the hospital.
View Article and Find Full Text PDFCureus
July 2025
General Medicine, Newcastle upon Tyne Hospitals, Newcastle upon Tyne, GBR.
Introduction Magnesium is essential for regulating cardiovascular, neuromuscular, and respiratory functions. Hypomagnesemia in older adults is often overlooked and insufficiently managed. Inadequate monitoring and correction of hypomagnesemia may leave old and frail patients more vulnerable to acute cognitive decline, which in some cases can be preventable.
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August 2025
Family Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.
Pellagra is a disease of niacin (vitamin B3) deficiency and is classically characterized by the triad of diarrhea, dermatitis, and dementia, and has the potential to cause death. Pellagra can be caused by either insufficient dietary intake or dysfunctional utilization of niacin. Because niacin can be found in nearly every food group (meat, dairy, vegetables, grains, etc.
View Article and Find Full Text PDFFront Pharmacol
August 2025
Department of Pharmacy, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Background: Pharmacologic agents with proposed neuroprotective properties are increasingly investigated; however, limited regulation and heterogeneous evidence raise concerns about their safety profiles. To establish a foundation for its safe clinical use, the data mining technology was used to investigate the safety warning signals of neuroprotective agent post-market approval.
Methods: The Jinan adverse event (AE) reporting system database was searched for AEs related to neuroprotective agents from January 2000 to March 2022.
Radiol Case Rep
November 2025
Department of Radiology, Hospital of Specialties, Mohammed V, Rabat, Morocco.
Tuberculous meningitis (TBM) is a severe form of tuberculosis that can lead to complications such as stroke, occurring in 13%-57% of cases. This report describes a 21-year-old man with no prior medical history who presented with headache, fever, and vomiting, followed by visual hallucinations, impaired alertness, and speech disturbances. Initial CT imaging revealed bilateral hypodense frontal lesions with poor contrast enhancement, and cerebrospinal fluid analysis indicated lymphocytic meningitis.
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