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http://dx.doi.org/10.1007/s12264-023-01148-0 | DOI Listing |
Neurosci Bull
March 2024
School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Neurobiol Aging
October 2018
Centre for Healthy Brain Ageing (CHeBA), University of New South Wales (UNSW) Australia, Sydney, New South Wales, Australia; School of Psychiatry, UNSW Australia, Sydney, New South Wales, Australia; Neuropsychiatric Institute, Prince of Wales Hospital, Randwick, New South Wales, Australia.
Altered inhibition-excitation balance is implicated in brain aging. We hypothesized that expression of 14 genes encoding proteins localized to synapses or interneurons would show age-related changes relative to 1 another in postmortem tissue from the prefrontal cortex of 37 individuals (18-78 years) and that synaptic or interneuron markers would be differentially correlated with human brain volumes across aging. The majority of genes examined were differentially expressed with age, most being downregulated.
View Article and Find Full Text PDFBehav Brain Res
April 2016
Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA. Electronic address:
Considering the limited information on the ability of chronic peripheral inflammation to induce behavioral alterations, including on their persistence after inflammatory stimuli termination and on associated neurochemical perturbations, this study assessed the effects of chronic (0.25 mg/kg; i.p.
View Article and Find Full Text PDF