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In the realm of machine vision, the convolutional neural network (CNN) is a frequently used and significant deep learning method. It is challenging to comprehend how predictions are formed since the inner workings of CNNs are sometimes seen as a black box. As a result, there has been an increase in interest among AI experts in creating AI systems that are easier to understand. Many strategies have shown promise in improving the interpretability of CNNs, including Class Activation Map (CAM), Grad-CAM, LIME, and other CAM-based approaches. These methods do, however, have certain drawbacks, such as architectural constraints or the requirement for gradient computations. We provide a simple framework termed Adaptive Learning based CAM (Adaptive-CAM) to take advantage of the connection between activation maps and network predictions. This framework includes temporarily masking particular feature maps. According to the Average Drop-Coherence-Complexity (ADCC) metrics, our method outperformed Score-CAM and another CAM-based activation map strategy in Residual Network-based models. With the exception of the VGG16 model, which witnessed a 1.94% decline in performance, the performance improvement spans from 3.78% to 7.72%. Additionally, Adaptive-CAM generates saliency maps that are on par with CAM-based methods and around 153 times superior to other CAM-based methods.
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http://dx.doi.org/10.1109/JBHI.2023.3329231 | DOI Listing |
JMIR Med Inform
September 2025
Department of Radiology, Air Force Medical Center, Air Force Medical University, Fucheng Road 30, Haidian District, Beijing, CN.
Background: Lateral malleolar avulsion fracture (LMAF) and subfibular ossicle (SFO) are distinct entities that both present as small bone fragments near the lateral malleolus on imaging, yet require different treatment strategies. Clinical and radiological differentiation is challenging, which can impede timely and precise management. On imaging, magnetic resonance imaging (MRI) is the diagnostic gold standard for differentiating LMAF from SFO, whereas radiological differentiation on computed tomography (CT) alone is challenging in routine practice.
View Article and Find Full Text PDFMol Divers
September 2025
Information Technology and Computing Applications, Vignan's Foundation for Science, Technology and Research (Deemed to be University), Guntur, India.
Nucleic Acids Res
September 2025
School of Software, Shandong University, Jinan 250101, Shandong, China.
Spatial transcriptomics (ST) reveals gene expression distributions within tissues. Yet, predicting spatial gene expression from histological images still faces the challenges of limited ST data that lack prior knowledge, and insufficient capturing of inter-slice heterogeneity and intra-slice complexity. To tackle these challenges, we introduce FmH2ST, a foundation model-based method for spatial gene expression prediction.
View Article and Find Full Text PDFJ Chem Phys
September 2025
National Synchrotron Radiation Laboratory, State Key Laboratory of Advanced Glass Materials, Anhui Provincial Engineering Research Center for Advanced Functional Polymer Films, University of Science and Technology of China, Hefei, Anhui 230029, China.
Polymer density is a critical factor influencing material performance and industrial applications, and it can be tailored by modifying the chemical structure of repeating units. Traditional polymer density characterization methods rely heavily on domain expertise; however, the vast chemical space comprising over one million potential polymer structures makes conventional experimental screening inefficient and costly. In this study, we proposed a machine learning framework for polymer density prediction, rigorously evaluating four models: neural networks (NNs), random forest (RF), XGBoost, and graph convolutional neural networks (GCNNs).
View Article and Find Full Text PDFJ Food Sci
September 2025
Faculty of Computing, Federal University of Uberlandia, Uberlândia, Brazil.
The coffee roasting process is a critical factor in determining the final quality of the beverage, influencing its flavour, aroma, and acidity. Traditionally, roast-level classification has relied on manual inspection, which is time-consuming, subjective, and prone to inconsistencies. However, advancements in machine learning (ML) and computer vision, particularly convolutional neural networks (CNNs), have shown great promise in automating and improving the accuracy of this process.
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