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http://dx.doi.org/10.21037/hbsn-23-372 | DOI Listing |
J Clin Ultrasound
September 2025
Second Department of Anesthesiology, Medical School, National and Kapodistrian University of Athens, NKUA, Athens, Greece.
Sonographic examination of major vessels can be a valuable bedside tool for perioperative hemodynamic assessment. In the present review, we present the anatomic and physiological aspects of internal jugular vein ultrasonography, its utility in assessing central venous pressure, intravascular volume status, fluid responsiveness, and its predictive value regarding post-spinal anesthesia hypotension. The existing literature is primarily comprised of small, observational studies with great heterogeneity in their methodology and shortcomings in data development and analysis, rendering the generalization of their results difficult to interpret for daily clinical practice.
View Article and Find Full Text PDFTher Innov Regul Sci
September 2025
Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Introduction: During the COVID-19 pandemic, regulatory and market access actions were taken to expedite the market entry of COVID-19 medicines. This study aims to (i) capture multi-stakeholder views on these actions, and (ii) provide recommendations for future-proofing routine and health-emergency frameworks.
Methods: Semi-structured interviews were conducted with policy makers/advisors (i.
Mol Psychiatry
September 2025
Department of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Epigenetic processes, such as DNA methylation, show potential as biological markers and mechanisms underlying gene-environment interplay in the prediction of mental health and other brain-based phenotypes. However, little is known about how peripheral epigenetic patterns relate to individual differences in the brain itself. An increasingly popular approach to address this is by combining epigenetic and neuroimaging data; yet, research in this area is almost entirely comprised of cross-sectional studies in adults.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
September 2025
Civil and Environmental Engineering Department, King Fahd University of Petroleum & Minerals, 31261, Dhahran, Saudi Arabia.
Concrete production significantly contributes to CO emissions and depletion of natural resources, leading to substantial environmental concerns. The integration of polymers into concrete has emerged as a promising innovative solution aimed at overcoming inherent limitations of traditional concrete, including brittleness, susceptibility to tracking, environmental degradation, and substantial ecological impacts. This systematic review thoroughly investigates the properties, sustainability implications, and practical challenges associated with polymer-based concrete (PBC), particularly focusing on polymer concrete composites (PCC) and polymer-modified concrete (PMC) detailing their composition, mechanical behavior, and durability.
View Article and Find Full Text PDF