Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

To urge nations worldwide to implement robust measures for enhancing human development and mitigating the pressures exerted on the planet by human activities in pursuit of sustainable development, this study encompasses 154 countries globally, using the seven major regions as focal points. Leveraging the Planetary Pressure Adjusted Human Development Index (PHDI) proposed by the United Nations Development Programme on December 15, 2020, as a metric for human development levels, this paper aims to standardize and internationally compare human development data from 1990 to 2021. Subsequently, employing the Theil index, the study assesses the global human development status across the seven regions to analyze spatial disparities in PHDI. Lastly, a comprehensive Generalized Diese Index Method (GDIM) is constructed to accurately reflect absolute and latent factors, dissecting the driving forces impacting global PHDI. The study explores critical pathways for high-quality human development within the harmonious coexistence between humanity and nature. It validates the robustness of GDIM results through a stepwise regression. Research findings indicate varying levels of PHDI development across regions, with a distinct spatial hierarchy evolving: higher human development levels in Europe and Eastern Europe, favorable levels in North and South America, similar levels in Oceania and Asia, and significant improvement potential in Africa. As globalization progresses, overall differences in PHDI gradually decrease; however, disparities persist between and within regions. Economic, technological, and per capita welfare effects consistently positively drive PHDI. In contrast, environmental pressure effects, social effects, per capita value-added effects, and output carbon intensity effects consistently exert hostile driving forces. Population size effects on PHDI show a fluctuating trend. Moreover, in terms of cumulative contribution values, the top three contributors to driving forces are economic, technological, and per capita welfare effects.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jenvman.2023.119292DOI Listing

Publication Analysis

Top Keywords

human development
32
driving forces
12
development
11
human
9
planetary pressure
8
development levels
8
economic technological
8
technological capita
8
capita welfare
8
welfare effects
8

Similar Publications

Objective: From October 18-20, 2022, the National Institutes of Health held a workshop to examine the state of the science concerning obesity interventions in adults to promote health equity. The workshop had three objectives: (1) Convene experts from key institutions and the community to identify gaps in knowledge and opportunities to address obesity, (2) generate recommendations for obesity prevention and treatment to achieve health equity, and (3) identify challenges and needs to address obesity prevalence and disparities, and develop a diverse workforce.

Methods: A three-day virtual convening.

View Article and Find Full Text PDF

Genetic factors associated with the co-occurrence of endometriosis with antiphospholipid syndrome (Review).

Exp Ther Med

October 2025

Section of Molecular Pathology and Human Genetics, Department of Internal Medicine, School of Medicine, University of Crete, 71003 Heraklion, Greece.

Immune-related factors may serve an important role in the development of endometriosis, considering the occurrence of substantial abnormalities in the immune system of women with endometriosis, including reduced T-cell reactivity and natural killer cell cytotoxicity, as well as increased numbers and activation of peritoneal macrophages. Moreover, women suffering from endometriosis are at a higher risk for developing various autoimmune diseases as comorbidities of endometriosis. Recent epidemiological data demonstrate that patients with endometriosis have a significantly higher risk (2.

View Article and Find Full Text PDF

Adeno-associated virus (AAV) vectors are widely used in gene therapy, particularly for liver-targeted treatments. However, predicting human-specific outcomes, such as transduction efficiency and hepatotoxicity, remains challenging. Reliable models are urgently needed to bridge the gap between preclinical studies and clinical applications.

View Article and Find Full Text PDF

Species-specific gene expression manipulation in humanized livers of chimeric mice via siRNA-encapsulated lipid nanoparticle treatment.

Mol Ther Methods Clin Dev

June 2025

Eisai Co., Ltd., Tsukuba Research Laboratories, 5-1-3, Tokodai, Tsukuba, Ibaraki 300-2635, Japan.

Liver-humanized chimeric mice (PXB-mice) are widely utilized for predicting human pharmacokinetics (PK) and as human disease models. However, residual metabolic activity of mouse hepatocytes in chimeric mice can interfere with accurate human PK estimation. Lipid nanoparticle (LNP)-formulated small interfering RNA (siRNA) treatment makes it possible to eliminate the shortcomings of chimeras and create new models.

View Article and Find Full Text PDF

Reconstructing bone defects remains a significant challenge in clinical practice, driving the urgent need for advanced artificial grafts that simultaneously promote vascularization and osteogenesis. Addressing the critical trade-off between achieving high porosity/strength and effective bioactivity at safe ion doses, we incorporated strontium (Sr) into β-tricalcium phosphate (β-TCP) scaffolds with a triply periodic minimal surface (TPMS) structure using digital light processing (DLP)-based three-dimensional (3D) printing. Systematically screening Sr concentrations (0-10 mol%), we identified 10 mol% as optimal, leveraging the synergy between the biomimetic TPMS architecture, providing exceptional mechanical strength (up to 1.

View Article and Find Full Text PDF