Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Assessing inorganic phosphate levels seems crucial in deciphering the biochemical state of organisms or tissues. The concentration of inorganic phosphate in blood is an order of magnitude smaller than in tissues and, on top of that, it is dynamically used to fill temporary gaps in tissues. This is the reason blood inorganic phosphate level is considered a poor proxy for tissue levels. Therefore, tissue biopsy seems to be the dominant method when assessing inorganic phosphate levels for instance in muscles. In this study, we attempted to derive a non-invasive biomarker for phosphate tissue levels. We analyzed surface electromyography signals taken during 31P spectroscopy of leg muscles in five adult pigs. We induced hypophosphatemia via 20 minutes-long hyperventilation. It turned out that the proportion of the amplitude of the low frequency band and the high frequency band is significantly (p=0.002) correlated with the relative phosphate levels. The electromyographic signal did not correlate significantly with pCO2 levels in the blood, suggesting that the changes in the signal are a result of inorganic phosphate levels, not hyperventilation. The results might lead to the development of a real-time phosphate fluctuations measurement procedure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.18388/abp.2020_6893 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
PI(3)P coordinates SNX17- and SNX27-dependent protein recycling for long-term synaptic plasticity.
J Cell Biol
November 2025
Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Two major protein recycling pathways have emerged as key regulators of enduring forms of synaptic plasticity, such as long-term potentiation (LTP), yet how these pathways are recruited during plasticity is unknown. Phosphatidylinositol-3-phosphate (PI(3)P) is a key regulator of endosomal trafficking and alterations in this lipid have been linked to neurodegeneration. Here, using primary hippocampal neurons, we demonstrate dynamic PI(3)P synthesis during chemical induction of LTP (cLTP), which drives coordinate recruitment of the SNX17-Retriever and SNX27-Retromer pathways to endosomes and synaptic sites.
View Article and Find Full Text PDFOil Well Stimulation of Dispersion-Penetration Agent and Plugging Removal Technology.
ACS Omega
September 2025
National Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu, Sichuan 610500, China.
Conventional acidizing struggles to remove complex, organic-rich scales in oil wells, and while strong organic solvents can help, their high cost and safety risks limit field use. To overcome these shortcomings, we developed a low-cost, safe permeability-enhanced-dispersion (PD) technique that first loosens and disperses the scale and then applies acid for thorough cleanup. The PD fluid (DL) contains a mutually soluble fatty alcohol amide phosphate dispersant (DL-F), ethanol, a surfactant blend, and a self-generating acid.
View Article and Find Full Text PDFTuning the grafting of phosphate groups onto Kraft lignin structures by varying the reaction parameters: phosphorylated lignin as an eco-friendly additive for epoxy resins.
Int J Biol Macromol
September 2025
Department of Organic and Inorganic Chemistry, Federal University of Ceará, 60440-900, Fortaleza, CE, Brazil. Electronic address:
Kraft lignin (KL) is a byproduct of the pulp and paper industry and has been extensively used in several high-value-added applications. The aim of this study was to evaluate the potential of phosphorylated Kraft lignins obtained by different reaction conditions (e.g.
View Article and Find Full Text PDFBioactive hydroxyapatite-sodium silicate waterglass reinforced with nanocollagen from Chitala ornata fish skin for bone engineering.
Int J Biol Macromol
September 2025
The Materials Engineering Department, Faculty of Engineering, Kasetsart University, Phaholyothin Rd., Bangkok 10900, Thailand. Electronic address:
A prototype bioactive calcium phosphate model-specifically hydroxyapatite (HA) derived from eggshells-was developed using a sodium silicate (NaSiO) solution as an inorganic binder, precursor, and reinforcing agent, in combination with collagen nanofibers for bone engineering applications. The sodium silicate solution, functioning as a waterglass adhesive, introduced cohesive forces within the hydroxyapatite matrix, thereby enhancing its physical, chemical, and mechanical properties. Eggshell-derived bioactive hydroxyapatite offers several advantages, including non-toxicity, biocompatibility, collagen adhesion, and the ability to mimic bone structure, making it suitable for tissue engineering.
View Article and Find Full Text PDFA sensitive smartphone-based method for measuring phosphate in biological samples and ATPase activities.
Talanta
August 2025
Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Biológica, Junín 956, Buenos Aires, Argentina; Laboratorio de Biofísica Molecular, Instituto de Química y Fisicoquímica Biológicas, UBA - CONICET, Junín 956, Buenos Aires, Argentina. Electronic address:
The quantification of orthophosphate is essential for applications like water quality assessment, soil fertility analysis, metabolic monitoring and enzyme activity evaluation. Chemical quantification methods include the reaction between orthophosphate and molybdate under acidic conditions to form 12-molybdophosphoric acid units, which auto-assembles forming nanometer size particles. The adsorption of malachite green to these nanoparticles allows their spectrophotometric detection constituting one of the most widely used methods to quantify phosphate.
View Article and Find Full Text PDF